Cognitive Function and Fatigue in Stable Multiple Sclerosis: EDSS and MRI Assessments Surpass Serum Biomarkers - Scorecard - MDSpire

Cognitive Function and Fatigue in Stable Multiple Sclerosis: EDSS and MRI Assessments Surpass Serum Biomarkers

  • By

  • Deborah K. Erhart

  • Luisa T. Balz

  • Roland Opfer

  • Lothar Spies

  • Franziska Bachhuber

  • Ioannis Vardakas

  • Daniela Taranu

  • Stefanie Jung

  • Tanja Fangerau

  • Makbule Senel

  • Kornelia Kreiser

  • Ingo Uttner

  • Dorothée Lulé

  • Hayrettin Tumani

  • April 17, 2026

  • 0 min

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Clinical Scorecard: Cognitive Function and Fatigue in Stable Multiple Sclerosis: EDSS and MRI Assessments Surpass Serum Biomarkers

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients with stable relapsing-remitting multiple sclerosis (RRMS).
Care Setting

Key Highlights

  • Cognitive impairment affects 34-65% of MS patients; fatigue affects up to 95%.

Guideline-Based Recommendations

Diagnosis

  • Utilize neuropsychological assessments, MRI, and serum biomarkers for evaluating cognitive impairment in MS.

Management

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Focus on cognitive assessments, MRI findings, and serum biomarkers.

        Clinical Best Practices

        • Incorporate both cognitive assessments, MRI findings, and serum biomarkers in routine evaluations of MS patients.

        References

        Original Source(s)

        Cognitive Function and Fatigue in Stable Multiple Sclerosis: EDSS and MRI Assessments Surpass Serum Biomarkers

        • by Deborah K. Erhart, Luisa T. Balz, Roland Opfer, Lothar Spies, Franziska Bachhuber, Ioannis Vardakas, Daniela Taranu, Stefanie Jung, Tanja Fangerau, Makbule Senel, Kornelia Kreiser, Ingo Uttner, Dorothée Lulé, Hayrettin Tumani

        • April 17, 2026

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