Phenotyping of isolated mesh associated pain secondary to continence mesh device insertion
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By
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Hawra Badri
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Karen Ward
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Richard Edmondson
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Fiona Reid
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June 17, 2026
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Clinical Scorecard: Characterization of Phenotypes in Isolated Mesh-Related Pain Following Continence Device Insertion
At a Glance
| Category | Detail |
|---|
| Condition | Isolated Mesh Associated Pain Syndrome (I-MAPS) |
| Key Mechanisms | Nociceptive, neuropathic, and nociplastic pain mechanisms |
| Target Population | Women with I-MAPS related to a single continence device |
| Care Setting | Quaternary-level mesh complications service |
Key Highlights
- 280 women presented with I-MAPS over 5 years
- 52% reported pre-existing pain-inducing conditions
- 55% exhibited neuropathic mediated pain
- TOT devices associated with higher PDQ scores than retropubic devices
- Moderate impact on daily activities and mental well-being
Guideline-Based Recommendations
Diagnosis
- Utilize pain body-mapping and validated questionnaires (PDQ, e PAQ) for pain phenotype assessment
Management
- Consider phenotype-specific treatment options based on pain classification
Monitoring & Follow-up
- Assess quality of life and mental well-being using EQ5D and WHO-5 wellbeing index
Risks
- Chronic pain associated with mesh devices can lead to functional disability and reduced mood
Patient & Prescribing Data
Women with I-MAPS related to single continence devices
Pain phenotyping may guide more effective treatment strategies
Clinical Best Practices
- Incorporate pain phenotyping in clinical assessments
- Monitor mental health and quality of life in patients with I-MAPS
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