Author Correction: Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS - Scorecard - MDSpire
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Correction: Scribble mis-localization drives adaptive resistance to KRAS G12C inhibitors via YAP-induced MRAS and feedback activation of MAPK signaling

  • By

  • Yuta Adachi

  • Ryo Kimura

  • Kentaro Hirade

  • Shogo Yanase

  • Yuki Nishioka

  • Natsumi Kasuga

  • Rui Yamaguchi

  • Hiromichi Ebi

  • October 19, 2026

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Clinical Scorecard: Correction: Scribble mis-localization drives adaptive resistance to KRAS G12C inhibitors via YAP-induced MRAS and feedback activation of MAPK signaling

At a Glance

CategoryDetail
ConditionClinical topic addressed by the source article: Correction
Key MechanismsMechanisms or clinical associations described in the source article.
Target PopulationPatients or participants described in the source article.
Care SettingResearch context: correction of figure and Source Data values in a study.

Key Highlights

  • Published online 5 June 2023.
  • The correction concerns Source Data for Extended Data Fig. 1f and its accompanying plot.
  • Three NCI-H358 snail control values were duplicated and substituted for the NCI-H358 ZEB1 control values.
  • The figure and Source Data were corrected in the article’s HTML and PDF versions.
  • The original figure is provided as Supplementary Information for comparison.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

          Patient & Prescribing Data

          Not applicable; the notice addresses a research-data correction and provides no patient population.

          No prescribing or treatment guidance is provided.

          Clinical Best Practices

          • The corrected figure and Source Data are available in the article’s HTML and PDF versions.

          Related Resources & Content

          Original Source(s)

          Author Correction: Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

          • by Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi

          • October 19, 2026

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