Editorial: The role of immune and stromal mediators in the formation of pre-metastatic and metastatic niches: the gateway to metastasis - Scorecard - MDSpire

Editorial: The role of immune and stromal mediators in the formation of pre-metastatic and metastatic niches: the gateway to metastasis

  • By

  • Michal A. Rahat

  • Dalit Barkan

  • Adit Ben-Baruch

  • June 18, 2026

  • 0 min

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Clinical Scorecard: The Influence of Immune and Stromal Factors on the Development of Pre-Metastatic and Metastatic Niches: Pathways to Metastasis

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients with various types of metastatic cancer, including breast, colorectal, and lung cancers.
Care Setting

Key Highlights

  • Add a highlight on the role of specific immune cells in treatment resistance.

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider combination therapies that target both tumor cells and the tumor microenvironment, such as immune checkpoint inhibitors with chemotherapy.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Combination therapies involving immune checkpoint inhibitors and targeted therapies may improve outcomes in breast, colorectal, and lung cancers.

        Clinical Best Practices

        • Include monitoring strategies for treatment response, such as imaging and biomarker assessments.

        Related Resources & Content

        Original Source(s)

        Editorial: The role of immune and stromal mediators in the formation of pre-metastatic and metastatic niches: the gateway to metastasis

        • by Michal A. Rahat, Dalit Barkan, Adit Ben-Baruch

        • June 18, 2026

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