Outcome of Patients with Single Ventricles who Initially did not Indicate Fontan Completion After Stage II Palliation - Scorecard - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Clinical Outcomes in Single Ventricle Patients Who Initially Did Not Pursue Fontan Completion Following Stage II Palliation

  • By

  • Carolin Niedermaier

  • Cornelius Przybilla

  • Thibault Schaeffer

  • Muneaki Matsubara

  • Christina Ruda

  • Jonas Palm

  • Nicole Piber

  • Peter Ewert

  • Jürgen Hörer

  • Masamichi Ono

  • July 13, 2026

Share

Clinical Scorecard: Clinical Outcomes in Single Ventricle Patients Who Initially Did Not Pursue Fontan Completion Following Stage II Palliation

At a Glance

CategoryDetail
ConditionUniventricular heart disease
Key MechanismsElevated pulmonary artery pressure, pulmonary artery stenosis, reduced ventricular function, significant atrioventricular valve regurgitation
Target PopulationInfants with univentricular hearts who underwent bidirectional cavopulmonary shunt
Care SettingSingle-center retrospective study

Key Highlights

  • Patients unable to undergo Fontan completion face high risks of heart failure and mortality.
  • Delayed Fontan completion may be possible after re-evaluation and appropriate interventions.
  • Key contraindications for Fontan completion include high pulmonary artery pressure and significant AV valve regurgitation.

Guideline-Based Recommendations

Diagnosis

  • Assessment of pulmonary artery pressure and ventricular function is critical for Fontan candidacy.

Management

  • Interventional therapies may improve candidacy for delayed Fontan completion.

Monitoring & Follow-up

  • Regular follow-up and re-assessment of cardiac function and anatomy are necessary.

Risks

  • Patients with high pulmonary artery pressure and reduced ventricular function have increased postoperative complications.

Patient & Prescribing Data

Infants with univentricular hearts post-bidirectional cavopulmonary shunt

Medical and interventional therapies can alter candidacy for Fontan completion.

Clinical Best Practices

  • Perform cardiac catheterization at 15 months for Fontan candidacy assessment.
  • Address significant AV valve regurgitation prior to Fontan completion.

Related Resources & Content

Original Source(s)

Outcome of Patients with Single Ventricles who Initially did not Indicate Fontan Completion After Stage II Palliation

  • by Carolin Niedermaier, Cornelius Przybilla, Thibault Schaeffer, Muneaki Matsubara, Christina Ruda, Jonas Palm, Nicole Piber, Peter Ewert, Jürgen Hörer, Masamichi Ono

  • July 13, 2026

Related Content

When Heart Failure Treatment Isn’t Enough: Signs It’s Time to Refer for Advanced Heart Failure Care

Advanced heart failure does not always present as a single defining event. Referring physicians may instead notice a pattern of worsening symptoms, recurrent hospitalizations or increasing difficulty maintaining a patient’s clinical stability.

  • by

  • August 28, 2026

  • 6 min
Disparities in the management of cardiogenic shock complicating acute myocardial infarction: a questionnaire survey in Beijing

FDA adds generic valganciclovir oral solution

 The new option is indicated for CMV prophylaxis in pediatric kidney and heart transplant recipients, as well as adult CMV retinitis and transplant prophylaxis.