The Keys to Opening Access to Clinical Trials - Scorecard - MDSpire
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Strategies for Enhancing Participation in Clinical Trials

  • By

  • Raymond U. Osarogiagbon

  • October 6, 2026

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Clinical Scorecard: Strategies for Enhancing Participation in Clinical Trials

At a Glance

CategoryDetail
ConditionClinical Trials in Oncology
Key MechanismsBarriers to participation include structural, clinical, and patient-level factors.
Target PopulationAdults with advanced or metastatic cancer receiving treatment in the US.
Care SettingOncology practices with available clinical trials.

Key Highlights

  • Only 5.2% of patients received a clinical study drug between 2011 and 2024.
  • 83.6% of trial enrollments were from 23.4% of physicians.
  • Structural barriers prevent 60% of treated patients from participating in trials.
  • Practices with high research engagement are more likely to enroll patients.
  • Patient-level variables accounted for 11.4% of trial participation variation.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

          Patient & Prescribing Data

          Adults with advanced or metastatic cancer.

          Limited access to clinical trials affects treatment options and outcomes.

          Clinical Best Practices

          • Develop clinical trials infrastructure at facilities serving socioeconomically disadvantaged populations.
          • Implement targeted interventions for practices with low trial participation.
          • Conduct qualitative evaluations of practices to identify barriers to trial access.

          Related Resources & Content

          Original Source(s)

          The Keys to Opening Access to Clinical Trials

          • by Raymond U. Osarogiagbon

          • October 6, 2026

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