Endoscopic versus open surgery for soft tissue vascular anomalies and benign tumors: a two-center propensity score-matched study - Scorecard - MDSpire

Endoscopic versus open surgery for soft tissue vascular anomalies and benign tumors: a two-center propensity score-matched study

  • By

  • Ming Li

  • Huaijie Wang

  • Zhengtuan Guo

  • Chong Xie

  • Weilong Lin

  • Peihua Wang

  • Weijia Yang

  • Lingling He

  • Lijuan Zhang

  • April 15, 2026

  • 0 min

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Clinical Scorecard: Comparative Analysis of Endoscopic and Open Surgical Techniques for Benign Tumors and Vascular Anomalies: A Propensity Score-Matched Study Across Two Centers

At a Glance

CategoryDetail
ConditionBenign soft tissue tumors and vascular anomalies
Key MechanismsComparison of soft-tissue endoscopic surgery (SOFTES) versus conventional open surgery (OS) focusing on operative safety, efficacy, and outcomes
Target PopulationPatients with benign soft tissue lesions suitable for surgical resection excluding those requiring complex reconstruction or involving vital structures
Care SettingSurgical treatment in specialized centers performing SOFTES and OS

Key Highlights

  • SOFTES demonstrated significantly lower estimated blood loss compared to OS (20 mL vs. 50 mL; p=0.001).
  • Operative duration was longer in SOFTES compared to OS (223 minutes vs. 173 minutes; p=0.008).
  • SOFTES had fewer wound complications such as wound dehiscence and flap necrosis compared to OS.

Guideline-Based Recommendations

Diagnosis

  • Careful patient selection excluding lesions requiring plastic skin removal, biopsy-only cases, CNS involvement, extensive deep muscular infiltration, or lesions involving vital nerves.
  • Use of propensity score matching to ensure comparable cohorts for surgical approach selection.

Management

  • SOFTES is a safe and effective minimally invasive surgical option for selected benign soft tissue tumors and vascular anomalies.
  • Open surgery remains an option but is associated with higher blood loss and wound complications.
  • Endoscopic surgery should be considered especially to reduce postoperative complications and improve cosmetic outcomes.

Monitoring & Follow-up

  • Monitor for focal skin burns which are more common in SOFTES.
  • Observe for wound dehiscence and flap necrosis, more frequent in OS.
  • Assess for nerve injury, postoperative bleeding, lymph drainage, sensory paralysis, infection, hematoma/seroma, and residual pain in both groups.

Risks

  • SOFTES carries a higher incidence of focal skin burns.
  • OS is associated with increased risk of wound dehiscence and flap necrosis.
  • No major complications observed in either group.

Patient & Prescribing Data

Patients undergoing surgical resection of benign soft tissue tumors and vascular anomalies at two centers

SOFTES offers reduced blood loss and fewer wound complications but requires longer operative time; residual pain improves or resolves postoperatively in both groups.

Clinical Best Practices

  • Select patients carefully to exclude those with lesions unsuitable for endoscopic or open approaches.
  • Employ propensity score matching or similar methods to reduce selection bias in comparative studies.
  • Use SOFTES to minimize blood loss and postoperative wound complications when feasible.
  • Prepare for longer operative times with SOFTES and monitor for skin burns.
  • Ensure thorough postoperative monitoring for nerve injury, infection, and wound healing complications.
  • Inform patients about the benefits and risks of both surgical options including cosmetic outcomes.

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