The Ratio of Creatinine to Body Weight as a Predictor of Mortality in Critically Ill Heart Failure Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database - Scorecard - MDSpire

The Ratio of Creatinine to Body Weight as a Predictor of Mortality in Critically Ill Heart Failure Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database

  • By

  • Dunlin Fang

  • Yanyi Huang

  • Jian Huang

  • Wanchun Hu

  • Changchang Zhang

  • Xing Liu

  • Zhenyu Shi

  • January 20, 2026

  • 0 min

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Clinical Scorecard: The Ratio of Creatinine to Body Weight as a Predictor of Mortality in Critically Ill Heart Failure Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database

At a Glance

CategoryDetail
ConditionHeart Failure (HF)
Key MechanismsCardiac dysfunction leading to multi-organ dysfunction and increased mortality risk.
Target PopulationCritically ill heart failure patients.
Care SettingIntensive Care Units (ICUs)

Key Highlights

  • Heart failure is a progressive disorder with a high global prevalence and significant mortality.
  • Creatinine-to-weight ratio (CWR) correlates with mortality risk in heart failure patients.
  • Critically ill heart failure patients experience markedly higher mortality compared to stable patients.
  • Obesity paradox observed in heart failure patients suggests overweight individuals may have better survival rates.
  • Urgent need for reliable prognostic tools for risk assessment in severe heart failure cases.

Guideline-Based Recommendations

Diagnosis

  • Utilize ICD-9 and ICD-10 codes for accurate identification of heart failure patients.

Management

  • Implement risk stratification based on creatinine-to-weight ratio for critically ill heart failure patients.

Monitoring & Follow-up

  • Regularly assess renal function and body weight in heart failure patients to evaluate prognosis.

Risks

  • Monitor for multi-organ dysfunction and life-threatening arrhythmias in critically ill heart failure patients.

Patient & Prescribing Data

Patients diagnosed with heart failure admitted to ICUs.

Elevated creatinine levels indicate higher mortality risk; consider CWR in treatment planning.

Clinical Best Practices

  • Utilize CWR as a prognostic tool in critically ill heart failure patients.
  • Ensure comprehensive data collection on demographics and comorbidities for accurate risk assessment.
  • Monitor vital signs and laboratory parameters closely in the ICU setting.

References

Original Source(s)

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