Delivery Reveals Brugada Syndrome in a 32-Year-Old Primigravida: A Case Study
By
Peng Liu
Ruilong Gao
Yaliu Yang
Zhengqin Zhai
Yifeng Zhou
September 9, 2026
Clinical Scorecard: Delivery Reveals Brugada Syndrome in a 32-Year-Old Primigravida: A Case Study
At a Glance
Category Detail
Condition Brugada Syndrome Key Mechanisms Electrophysiological imbalance between inward depolarising and outward repolarising currents, leading to increased vulnerability to arrhythmias. Target Population Women, particularly during the peripartum period. Care Setting Postpartum care following vaginal delivery.
Key Highlights
Previously asymptomatic woman developed ventricular fibrillation postpartum. ECG showed spontaneous type 1 Brugada pattern after resuscitation. No structural heart disease identified; electrolyte imbalances noted. Implantable cardioverter-defibrillator placed for secondary prevention. No arrhythmic episodes recorded during 18 months of follow-up. Guideline-Based Recommendations
Diagnosis
ECG findings of coved ST-segment elevation and T-wave inversion in right precordial leads. Management
Immediate defibrillation and CPR for ventricular fibrillation. Consideration of implantable cardioverter-defibrillator for secondary prevention. Monitoring & Follow-up
Scheduled outpatient device interrogations to monitor for arrhythmic episodes. Risks
Potential for unmasking of latent Brugada syndrome during pregnancy and postpartum period. Patient & Prescribing Data
Primigravida women with no prior symptoms or family history of arrhythmias.
Epidural ropivacaine may contribute to unmasking Brugada syndrome.
Clinical Best Practices
Recognize the potential for concealed channelopathies during peripartum cardiac events. Monitor electrolyte levels in postpartum patients, especially those with arrhythmias. Related Resources & Content
