Reframing precision nutrition in irritable bowel syndrome: a mechanism-informed conceptual framework for responder prediction and clinical translation
By
Ya Zhou
Zhen Li
Yuzhou Chu
Zhijia Zhou
Tao Zhang
Ning Yi
Wuquan Sun
Juntao Yan
Zhen Yan
Anning Zhu
May 29, 2026
Clinical Scorecard: Rethinking Precision Nutrition for Irritable Bowel Syndrome: A Mechanism-Based Framework for Predicting Patient Response and Clinical Application
At a Glance
Category Detail
Condition Key Mechanisms Gut-brain interaction, dysregulated signaling, altered microbial ecology linked to IBS pathophysiology. Target Population Care Setting
Key Highlights
Individual variability in dietary response is crucial for effective management. Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Monitor adherence to dietary interventions and capture symptom response using specific metrics. Risks
Patient & Prescribing Data
Patients with IBS, including subtypes IBS-D, IBS-C, and IBS-M.
Individual dietary strategies should be tailored based on baseline microbiome patterns and patient-specific factors.
Clinical Best Practices
Integrate patient education regarding dietary changes into clinical practice. Related Resources & Content
