Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review - Scorecard - MDSpire

Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review

  • By

  • Zilin Wang

  • Shaowu Zeng

  • Qiaorong Zhou

  • Jujiang Guo

  • July 6, 2026

  • 0 min

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Clinical Scorecard: Bilateral Acute Mastitis in a Lactating Woman as a Presentation of Metastatic Malignant Melanoma: A Case Study and Review of Existing Literature

At a Glance

CategoryDetail
ConditionMetastatic Malignant Melanoma
Key MechanismsHigh metastatic potential of malignant melanoma, mimicking benign inflammatory conditions.
Target PopulationPostpartum women presenting with breast symptoms.
Care SettingMaternal and Child Health Hospital

Key Highlights

  • Bilateral breast metastasis from melanoma is exceptionally rare.
  • Initial misdiagnosis as severe lactational mastitis led to delayed diagnosis.
  • Patient exhibited rapidly progressive disease, failing multiple therapies.
  • Emphasizes the need for thorough history-taking and skin examination.
  • Highlights diagnostic challenges in postpartum breast presentations.

Guideline-Based Recommendations

Diagnosis

  • Consider metastatic disease in atypical breast presentations.
  • Utilize imaging and biopsy for definitive diagnosis.

Management

  • Sequential targeted therapy, immunotherapy, and chemotherapy may be required.

Monitoring & Follow-up

  • Regular follow-up for disease progression and treatment response.

Risks

  • High risk of misdiagnosis in postpartum women with breast symptoms.

Patient & Prescribing Data

Postpartum women with breast swelling and pain.

Aggressive treatment may be necessary due to rapid disease progression.

Clinical Best Practices

  • Maintain a high index of suspicion for malignancy in postpartum breast conditions.
  • Conduct comprehensive skin examinations in patients with a history of melanoma.

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