Exercise habits and the risk of cardiovascular disease among adults with overweight or obesity: a longitudinal cohort analysis
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By
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Kai Mu
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Yanan Qiao
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Ruilang Lin
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Yongfu Yu
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Min Zhao
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Costan G. Magnussen
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Bo Xi
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February 16, 2026
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Clinical Scorecard: Exercise habits and the risk of cardiovascular disease among adults with overweight or obesity: a longitudinal cohort analysis
At a Glance
| Category | Detail |
| Condition | Cardiovascular Disease (CVD) |
| Key Mechanisms | Elevated BMI as a modifiable risk factor; physical activity reduces CVD risk. |
| Target Population | Adults aged 40-73 years with overweight or obesity (BMI ≥ 25 kg/m2). |
| Care Setting | Community-based cohort study utilizing accelerometer data. |
Key Highlights
- CVD accounts for approximately 19.91 million deaths globally in 2021.
- Physical activity is critical in mitigating CVD risk in overweight or obese individuals.
- Concentrated activity patterns may provide similar CVD risk reductions as regularly distributed activity.
- Approximately 75% of adults do not meet recommended physical activity guidelines.
- Accelerometer-based data provides objective assessment of physical activity levels.
Guideline-Based Recommendations
Diagnosis
- Utilize ICD-10 codes for CVD diagnosis from hospital records.
Management
- Encourage at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic physical activity weekly.
Monitoring & Follow-up
- Assess physical activity levels using accelerometry for objective measurement.
Risks
- Higher prevalence of CVD subtypes among individuals with overweight or obesity.
Patient & Prescribing Data
Adults with overweight or obesity aged 40-73 years.
Concentrated physical activity regimens may enhance adherence to exercise recommendations.
Clinical Best Practices
- Promote progressive dose-escalation of aerobic exercise for health benefits.
- Encourage consistent distribution of physical activity throughout the week.
- Address perceived time constraints as barriers to physical activity adherence.
References