HoLEP using a 21 Fr internal urethrotomy sheath, a feasible alternative to MiLEP in resource-limited settings - Scorecard - MDSpire

HoLEP using a 21 Fr internal urethrotomy sheath, a feasible alternative to MiLEP in resource-limited settings

  • By

  • Aykut Aykaç

  • Coşkun Kaya

  • Mustafa Sungur

  • Mehmet Erhan Aydın

  • June 27, 2026

  • 0 min

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Clinical Scorecard: Evaluating the Use of a 21 Fr Internal Urethrotomy Sheath for HoLEP as a Viable Option to MiLEP in Resource-Constrained Environments

At a Glance

CategoryDetail
ConditionBenign Prostatic Hyperplasia (BPH)
Key MechanismsHolmium laser enucleation of the prostate (HoLEP) using a modified low-caliber technique to reduce urethral trauma.
Target PopulationPatients aged ≥ 50 years with LUTS refractory to medical therapy and prostate volume ≥ 35 mL.
Care SettingEndourology units in resource-constrained environments.

Key Highlights

  • HoLEP is effective for large prostates and has a low bleeding risk.
  • Modified low-caliber HoLEP (mLC-HoLEP) uses a 21 Fr sheath to minimize urethral trauma.
  • Urethral stricture rates after standard HoLEP range from 2% to 5%.
  • mLC-HoLEP may provide similar outcomes to standard HoLEP without the need for specialized equipment.
  • Study included 47 patients undergoing mLC-HoLEP and 48 matched controls undergoing standard HoLEP.

Guideline-Based Recommendations

Diagnosis

  • Patients with LUTS should be evaluated for BPH, especially if symptoms are refractory to medical therapy.

Management

  • HoLEP is recommended for surgical treatment of BPH, particularly for larger prostate volumes.

Monitoring & Follow-up

  • Postoperative follow-up should include assessment of continence status and urethral stricture formation.

Risks

  • Potential risks include urethral stricture formation and transient urinary incontinence.

Patient & Prescribing Data

Men aged ≥ 50 years with BPH and LUTS.

mLC-HoLEP may be a safe and effective alternative to standard HoLEP in resource-limited settings.

Clinical Best Practices

  • Utilize available instruments to perform mLC-HoLEP in settings lacking specialized equipment.
  • Ensure proper patient selection based on inclusion and exclusion criteria.

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