Recognizing anxiety and depression in cancer patients based on speech and facial expressions
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By
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Na Xu
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Tao Wu
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Li Sun
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Ping Xin
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Xu Tan
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Na Luo
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Yi Liu
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May 14, 2026
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Clinical Scorecard: Identifying Anxiety and Depression in Cancer Patients Through Speech Patterns and Facial Cues
At a Glance
| Category | Detail |
| Condition | Anxiety and Depression in Cancer Patients |
| Key Mechanisms | Multimodal fusion approach utilizing speech and facial expression analysis. |
| Target Population | Clinically diagnosed cancer patients. |
| Care Setting | Oncological treatment settings. |
Key Highlights
- Depression prevalence among cancer survivors is 33.16%; anxiety prevalence is 30.55%.
- Traditional assessments often overlook psychological distress in 30% to 50% of patients.
- The multimodal model achieved an F1 value of 0.85 for depression and 0.74 for anxiety.
- Utilizes speech and facial cues as digital biomarkers for objective screening.
- Highlights the need for noninvasive, efficient psychological assessments.
Guideline-Based Recommendations
Diagnosis
- Implement multimodal assessments to enhance detection of anxiety and depression.
Management
- Integrate psychological support into routine oncological care.
Monitoring & Follow-up
- Use speech and facial expression analysis for ongoing psychological status evaluation.
Risks
- Undiagnosed anxiety and depression can lead to increased cancer-related complications and mortality.
Patient & Prescribing Data
Cancer patients experiencing psychological distress.
Objective screening methods can improve identification and management of mental health issues.
Clinical Best Practices
- Adopt multimodal frameworks for psychological assessments in cancer care.
- Train healthcare providers to recognize non-verbal cues of distress.
- Encourage the use of digital biomarkers to reduce stigma in mental health reporting.
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