Survey on Real-World Interventions and Strategies for Treat-to-Target Approaches in Psoriasis Management in Canada
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By
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Jensen Yeung
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Parbeer Grewal
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Perla Lansang
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Ron Vender
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Marni Wiseman
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Rami Abou Zeinab
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Maxime Barakat
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Vimal H. Prajapati
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April 16, 2026
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Clinical Scorecard: Survey on Real-World Interventions and Strategies for Treat-to-Target Approaches in Psoriasis Management in Canada
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Treat-to-target (T2T) approach using validated assessment tools (PASI, BSA, PGA, DLQI), emphasizing patient-reported outcomes. |
| Target Population | |
| Care Setting | |
Key Highlights
- 73.3% of patients achieved treatment targets
- 98.4% of patients meeting targets continued biologic therapy
- Nearly half of patients not meeting targets remained on treatment, influenced by shared decision-making
- Importance of individualized care and patient quality of life
- Canadian T2T criteria require concordance across multiple domains for treatment success
Guideline-Based Recommendations
Diagnosis
- Use of PASI, BSA, PGA, and DLQI for assessment
Management
- Implement T2T approach for treatment decisions
- Develop individualized treatment plans based on patient preferences
Monitoring & Follow-up
- Regular evaluations of treatment response using validated tools
Risks
- Consider potential benefits versus risks when modifying therapy
Patient & Prescribing Data
Adults with moderate-to-severe plaque psoriasis
Treatment decisions based on clinical judgment and patient consultation
Clinical Best Practices
- Adopt a structured hierarchy in treatment target assessment
- Incorporate patient-reported outcomes in treatment evaluations
- Ensure regular follow-ups to assess treatment efficacy
References
