Ultrasound-guided erector spinae plane block versus serratus anterior plane block for analgesia and respiratory function in patients with multiple rib fractures: a large-sample, single-center, randomized, double-blind, controlled trial - Scorecard - MDSpire

Ultrasound-guided erector spinae plane block versus serratus anterior plane block for analgesia and respiratory function in patients with multiple rib fractures: a large-sample, single-center, randomized, double-blind, controlled trial

  • By

  • Zhiliang Tang

  • Lina Zhou

  • June 5, 2026

  • 0 min

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Clinical Scorecard: Comparison of Ultrasound-Guided Erector Spinae Plane Block and Serratus Anterior Plane Block for Pain Relief and Respiratory Function in Patients with Multiple Rib Fractures: A Large-Scale, Single-Center, Randomized, Double-Blind Study

At a Glance

CategoryDetail
ConditionMultiple Rib Fractures
Key MechanismsUltrasound-guided erector spinae plane block (ESPB) and serratus anterior plane block (SAPB) for analgesia
Target PopulationPatients with unilateral multiple rib fractures
Care SettingEmergency and trauma centers

Key Highlights

  • ESPB demonstrated significantly lower 24-h pain AUC compared to SAPB (mean difference −17.78, p < 0.001)
  • ESPB reduced 24-h opioid consumption and improved QoR-15 scores (both p < 0.01)
  • Both groups showed significant within-group improvement in respiratory function parameters
  • Safety profiles and complication rates were comparable between ESPB and SAPB
  • Analgesic superiority of ESPB was more pronounced in patients with ≤5 fractures

Guideline-Based Recommendations

Diagnosis

  • Identify patients with unilateral multiple rib fractures

Management

  • Consider ESPB as a first-line regional analgesic technique for better pain control

Monitoring & Follow-up

  • Monitor pain scores, opioid consumption, and respiratory function post-intervention

Risks

  • Be aware of potential complications associated with rib fractures, such as pneumonia and respiratory failure

Patient & Prescribing Data

158 eligible patients with unilateral multiple rib fractures

0.375% ropivacaine used for both ESPB and SAPB

Clinical Best Practices

  • Utilize ultrasound guidance for performing ESPB and SAPB
  • Evaluate fracture characteristics to tailor analgesic technique selection
  • Implement multimodal analgesia to minimize opioid use

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