New diagnosis of diabetes in patients with myocardial infarction or stroke: a systematic review and meta-analysis - Scorecard - MDSpire

New diagnosis of diabetes in patients with myocardial infarction or stroke: a systematic review and meta-analysis

  • By

  • Marwa Douelrachad

  • Alexander Thistle

  • Hibo Rijal

  • Ari Ochuba

  • Calvin Ke

  • Charlotte Lee

  • Manav V Vyas

  • May 13, 2025

  • 0 min

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Clinical Scorecard: Incidence of Newly Diagnosed Diabetes Among Patients Hospitalized for Myocardial Infarction or Stroke: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionNewly diagnosed diabetes (NDD) in patients hospitalized for acute myocardial infarction (MI) or stroke
Key MechanismsDiabetes diagnosis during index hospitalization using oral glucose tolerance test (OGTT), haemoglobin A1c (HbA1c), or both
Target PopulationAdult patients hospitalized for acute MI or stroke without previously known diabetes
Care SettingHospital inpatient setting during acute MI or stroke admission

Key Highlights

  • Approximately 16.0% of patients with MI and 15.3% of patients with stroke receive a new diagnosis of diabetes during hospitalization.
  • The proportion of newly diagnosed diabetes has remained stable over the past 30 years.
  • Use of oral glucose tolerance test yields a higher detection rate of new diabetes compared to HbA1c alone.

Guideline-Based Recommendations

Diagnosis

  • Screen all eligible patients hospitalized for MI or stroke for diabetes to identify undiagnosed cases.
  • Consider using oral glucose tolerance test in addition to HbA1c to improve diabetes detection rates.

Management

  • Early identification of diabetes during hospitalization may enable timely intervention to reduce cardiovascular risk.
  • Manage newly diagnosed diabetes patients with appropriate cardiovascular risk reduction strategies.

Monitoring & Follow-up

  • Monitor patients with newly diagnosed diabetes for cardiovascular disease recurrence and mortality risk.
  • Standardize diabetes screening protocols in hospitalized patients with MI or stroke.

Risks

  • Patients with newly diagnosed diabetes at the time of MI or stroke have higher risk of cardiovascular recurrence and death compared to those without diabetes.
  • Potential missed opportunities for early diabetes diagnosis and prevention of cardiovascular events if screening is inadequate.

Patient & Prescribing Data

Adults hospitalized for acute myocardial infarction or stroke without previously known diabetes

Identification of new diabetes cases during hospitalization highlights the need for improved screening and subsequent management to prevent recurrent cardiovascular events.

Clinical Best Practices

  • Implement routine diabetes screening for all patients admitted with MI or stroke.
  • Use standardized diagnostic criteria and testing methods, preferably including OGTT, to improve detection accuracy.
  • Recognize newly diagnosed diabetes as a significant risk factor for cardiovascular disease recurrence and mortality.
  • Integrate diabetes management into post-MI and post-stroke care pathways to optimize outcomes.

References

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