Association Between Systemic Immune-Inflammation Index and Postoperative Optical Quality in the Early Recovery Phase After Cataract Surgery: A Retrospective Study - Scorecard - MDSpire

Association Between Systemic Immune-Inflammation Index and Postoperative Optical Quality in the Early Recovery Phase After Cataract Surgery: A Retrospective Study

  • By

  • Zang, Huaixiao

  • Shi, Dong

  • May 25, 2026

  • 0 min

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Clinical Scorecard: Relationship Between Preoperative Systemic Immune-Inflammation Index and Early Postoperative Optical Quality Following Cataract Surgery: A Retrospective Analysis

At a Glance

CategoryDetail
ConditionCataract Surgery Recovery
Key MechanismsSystemic inflammation as a factor influencing postoperative recovery
Target PopulationPatients undergoing phacoemulsification cataract surgery
Care SettingRetrospective analysis of surgical outcomes

Key Highlights

  • Higher preoperative log2-SII associated with lower internal MTF average height at 1 week and 1 month post-surgery
  • No significant association found at 1 day post-surgery
  • Low-SII group showed better internal Strehl ratio and lower higher-order aberrations at 1 month
  • Postoperative visual acuity comparable between groups
  • Systemic inflammatory status may contribute to variability in early optical recovery

Guideline-Based Recommendations

Diagnosis

  • Assess preoperative systemic immune-inflammation index (SII) in cataract surgery candidates

Management

  • Monitor early postoperative optical quality using internal modulation transfer function (MTF) metrics

Monitoring & Follow-up

  • Evaluate changes in optical quality at 1 week and 1 month post-surgery

Risks

  • Higher preoperative SII may indicate less favorable early postoperative outcomes

Patient & Prescribing Data

110 patients who underwent uneventful phacoemulsification with monofocal intraocular lens implantation

Systemic inflammatory status may influence optical recovery despite similar visual acuity

Clinical Best Practices

  • Consider systemic inflammation in preoperative assessments
  • Utilize MTF metrics for evaluating postoperative outcomes

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