Integrating Double-Balloon Enteroscopy into the Diagnostic Pathway for Suspected Small Bowel Crohn’s Disease: A Retrospective Study from a Tertiary Care Center - Scorecard - MDSpire

Integrating Double-Balloon Enteroscopy into the Diagnostic Pathway for Suspected Small Bowel Crohn’s Disease: A Retrospective Study from a Tertiary Care Center

  • By

  • Thomas Sheehan

  • Cormac Hegarty

  • Roisin Connaughton

  • Barry Hall

  • Orlaith B. Kelly

  • April 1, 2026

  • 0 min

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Clinical Scorecard: Integrating Double-Balloon Enteroscopy into the Diagnostic Pathway for Suspected Small Bowel Crohn’s Disease: A Retrospective Study from a Tertiary Care Center

At a Glance

CategoryDetail
ConditionSuspected Small Bowel Crohn’s Disease
Key MechanismsSBCE for non-invasive assessment; DBE for histological confirmation and therapeutic intervention.
Target PopulationPatients referred for suspected small bowel Crohn’s disease.
Care SettingTertiary referral center.

Key Highlights

  • SBCE established or excluded inflammatory bowel disease in 70% of patients.
  • DBE confirmed Crohn’s disease in 21% of patients undergoing the procedure.
  • DBE referral was predicted by increasing age and diagnostic uncertainty on SBCE.
  • SBCE was the initial investigation in 90.8% of cases.
  • DBE should be reserved for cases needing histological confirmation or therapeutic intervention.

Guideline-Based Recommendations

Diagnosis

  • Use SBCE as the first-line investigation for suspected small bowel Crohn’s disease.
  • Consider DBE for diagnostic clarification or when histological confirmation is needed.

Management

  • DBE can be used for therapeutic interventions such as stricture dilatation.

Monitoring & Follow-up

  • Monitor for capsule retention in patients with suspected stricturing disease.

Risks

  • Capsule retention rates range from 0–5.4% in suspected Crohn’s disease.

Patient & Prescribing Data

Patients with suspected small bowel Crohn’s disease referred for SBCE.

DBE may lead to changes in clinical management for a significant proportion of patients.

Clinical Best Practices

  • Utilize SBCE for initial assessment before considering DBE.
  • Ensure appropriate patient selection to maximize diagnostic yield.

References

Original Source(s)

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