Neurodevelopmental outcomes of children born to diabetic mothers in the Qatari population: a retrospective study
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By
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Razan M Masri
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Mohammad A A Bayoumi
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Rasha I Amin
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Hafsa O A Alsharif
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Amna Musa
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Ahmad S Mudrek
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Basma A M R Selim
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Prem Chandra
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Samah Elshaar
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May 22, 2026
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Clinical Scorecard: Neurodevelopmental Effects in Offspring of Diabetic Mothers within the Qatari Population: A Retrospective Analysis
At a Glance
| Category | Detail |
|---|
| Condition | Maternal Diabetes and Neurodevelopmental Outcomes |
| Key Mechanisms | Intrauterine hyperglycaemia, insulin metabolism disturbances, oxidative stress, and epigenetic modifications. |
| Target Population | Children born to Qatari mothers with gestational or pre-pregnancy diabetes. |
| Care Setting | Women’s Wellness and Research Center and Rumailah Hospital, Hamad Medical Corporation, Qatar. |
Key Highlights
- 23.8% of children were born to mothers with gestational diabetes.
- Higher odds of autism and speech delay were observed in children of mothers with gestational diabetes.
- No significant associations found for gross or fine motor delays.
- Study emphasizes the need for effective diabetes management during pregnancy.
- Calls for further longitudinal research on neurodevelopmental outcomes.
Guideline-Based Recommendations
Diagnosis
- Screen all pregnant women for diabetes at the first antenatal care visit.
Management
- Effective management of gestational diabetes is crucial for maternal and neonatal outcomes.
Monitoring & Follow-up
- Monitor neurodevelopmental outcomes in children born to mothers with diabetes.
Risks
- Maternal diabetes is associated with increased risks of adverse perinatal outcomes.
Patient & Prescribing Data
Full-term children born in 2017 to Qatari mothers.
Management of gestational diabetes may influence neurodevelopmental outcomes.
Clinical Best Practices
- Implement routine screening for gestational diabetes in pregnant women.
- Ensure effective prenatal management of diabetes to optimize outcomes.
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