Neurodevelopmental Effects in Offspring of Diabetic Mothers within the Qatari Population: A Retrospective Analysis
By
Razan M Masri
Mohammad A A Bayoumi
Rasha I Amin
Hafsa O A Alsharif
Amna Musa
Ahmad S Mudrek
Basma A M R Selim
Prem Chandra
Samah Elshaar
May 22, 2026
Clinical Scorecard: Neurodevelopmental Effects in Offspring of Diabetic Mothers within the Qatari Population: A Retrospective Analysis
At a Glance
Category Detail
Condition Maternal Diabetes and Neurodevelopmental Outcomes Key Mechanisms Intrauterine hyperglycaemia, insulin metabolism disturbances, oxidative stress, and epigenetic modifications. Target Population Children born to Qatari mothers with gestational or pre-pregnancy diabetes. Care Setting Women’s Wellness and Research Center and Rumailah Hospital, Hamad Medical Corporation, Qatar.
Key Highlights
23.8% of children were born to mothers with gestational diabetes. Higher odds of autism and speech delay were observed in children of mothers with gestational diabetes. No significant associations found for gross or fine motor delays. Study emphasizes the need for effective diabetes management during pregnancy. Calls for further longitudinal research on neurodevelopmental outcomes. Guideline-Based Recommendations
Diagnosis
Screen all pregnant women for diabetes at the first antenatal care visit. Management
Effective management of gestational diabetes is crucial for maternal and neonatal outcomes. Monitoring & Follow-up
Monitor neurodevelopmental outcomes in children born to mothers with diabetes. Risks
Maternal diabetes is associated with increased risks of adverse perinatal outcomes. Patient & Prescribing Data
Full-term children born in 2017 to Qatari mothers.
Management of gestational diabetes may influence neurodevelopmental outcomes.
Clinical Best Practices
Implement routine screening for gestational diabetes in pregnant women. Ensure effective prenatal management of diabetes to optimize outcomes. Related Resources & Content
