Giant sellar aneurysm presenting with arginine vasopressin deficiency: a rare case report
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By
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Xiaolong Zhang
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Pengfei Wang
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Baogen Pan
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June 3, 2026
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Clinical Scorecard: Uncommon Presentation of a Giant Sellar Aneurysm with Arginine Vasopressin Deficiency: A Case Study
At a Glance
| Category | Detail |
|---|
| Condition | Giant Sellar Aneurysm |
| Key Mechanisms | Compression of the pituitary gland leading to diabetes insipidus and hypopituitarism. |
| Target Population | Adults, particularly those with atypical symptoms of sellar mass lesions. |
| Care Setting | Multidisciplinary clinical setting. |
Key Highlights
- Giant sellar aneurysms can present with diabetes insipidus as the primary symptom.
- Differential diagnosis for sellar masses should include aneurysms.
- Successful management involved multidisciplinary collaboration.
- Postoperative outcomes included significant improvement in visual acuity and diabetes insipidus symptoms.
Guideline-Based Recommendations
Diagnosis
- Consider aneurysms in the differential diagnosis of sellar region masses.
Management
- Utilize intravenous desmopressin for diabetes insipidus management.
- Perform cerebral angiography for confirmation of aneurysm.
Monitoring & Follow-up
- Regular follow-up for endocrine hormone levels and related symptoms.
Risks
- Potential misdiagnosis as pituitary adenomas due to atypical presentations.
Patient & Prescribing Data
A 60-year-old woman with a history of hypertension.
Postoperative hormone replacement therapy included levothyroxine and hydrocortisone.
Clinical Best Practices
- Conduct comprehensive imaging studies for accurate diagnosis.
- Engage in multidisciplinary discussions for complex cases.
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