Comparative effects of structured exercise protocols on depression and anxiety symptoms: a network meta-analysis - Scorecard - MDSpire

Comparative effects of structured exercise protocols on depression and anxiety symptoms: a network meta-analysis

  • By

  • Zhiyuan Zhang

  • Fengyun Li

  • Can Han

  • Wenkun Song

  • Sifan Pu

  • June 8, 2026

  • 0 min

Share

Clinical Scorecard: Evaluating the Impact of Various Structured Exercise Regimens on Symptoms of Depression and Anxiety: A Network Meta-Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsExercise modalities improve mood disorders through distinct physiological and psychological mechanisms, including endorphin release and enhanced self-efficacy.
Target Population
Care Setting

Key Highlights

  • 22 studies with 1,830 participants were included in the analysis, with yoga ranked first based on SUCRA scores for both depression and anxiety symptom improvement.
  • All exercise modalities demonstrated significant improvements in depressive and anxiety symptoms, with no statistically significant differences in efficacy among yoga, moderate-intensity continuous training, and high-intensity interval training.
  • Subgroup analyses indicated larger effect sizes in the elderly group (≥60 years).

Guideline-Based Recommendations

Diagnosis

    Management

    • Incorporate structured exercise modalities such as yoga, HIIT, and MICT in treatment plans, as well as Tai Chi and Pilates.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Exercise interventions, including yoga, HIIT, and MICT, are safe, cost-effective, and can improve mood without pharmacological side effects.

        Clinical Best Practices

        • Develop individualized exercise regimens based on patient symptom clusters, preferences, and safety profiles.

        Related Resources & Content

        Original Source(s)

        Related Content