Prediction model for risk of multiple organ dysfunction syndrome in wasp sting patients: development and validation
By
Hongmei Dai
Dongmei Liu
Li Yang
Jiawei Chen
Xiaogang Du
June 25, 2026
Clinical Scorecard: Risk Assessment Model for Multiple Organ Dysfunction Syndrome in Patients with Wasp Stings: Creation and Evaluation
At a Glance
Category Detail
Condition Multiple Organ Dysfunction Syndrome (MODS) Key Mechanisms Systemic inflammatory response syndrome (SIRS) triggered by wasp venom leading to organ dysfunction. Target Population Patients with wasp stings. Care Setting Emergency medicine and intensive care.
Key Highlights
Developed a nomogram-based prediction model for MODS after wasp stings. Identified independent risk factors: age, time to admission, pleural effusion, RALE score, MPV/PLT, and SIRI. Model showed an AUC of 0.828, indicating good predictive ability. Guideline-Based Recommendations
Diagnosis
Assess clinical characteristics and laboratory parameters to identify MODS. Management
Initiate timely interventions to prevent progression to multi-organ failure. Monitoring & Follow-up
Regularly evaluate risk factors and clinical status in patients with wasp stings. Risks
MODS has a death rate exceeding 40% in affected patients. Patient & Prescribing Data
324 wasp sting patients, with 90 developing MODS.
Early identification of high-risk patients is crucial for improving outcomes.
Clinical Best Practices
Utilize the nomogram for rapid bedside assessment of MODS risk. Integrate multiple clinical indicators for comprehensive risk evaluation. Related Resources & Content
