Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle - Scorecard - MDSpire

Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle

  • By

  • Xiaorui Zhao

  • Ruiyu Zhang

  • Tong Sun

  • Yifei Yuan

  • Yu Zhang

  • Yueguo Chen

  • February 11, 2026

  • 0 min

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Clinical Scorecard: Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients with keratoconus, particularly adolescents and young adults (ages 12-30).
Care Setting

Key Highlights

  • significance

Guideline-Based Recommendations

Diagnosis

    Management

    • Regular monitoring of corneal parameters and visual acuity.
    • Consideration of hormonal influences in treatment planning for both male and female patients.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Hormonal profiles may provide insights into individual disease progression and management, potentially guiding personalized treatment strategies.

        Clinical Best Practices

        • Conduct comprehensive ophthalmological examinations including tomographic and biomechanical assessments.
        • Standardize hormone level measurements to control for diurnal variation.
        • Educate patients on the potential impact of environmental and hormonal factors on keratoconus.
        • Establish follow-up frequency based on hormonal assessments.

        References

        Original Source(s)

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