Dietary patterns among individuals with plasma cell disorders– opportunities for targeted interventions

Category	Detail
Condition	Plasma Cell Disorders (MGUS, SMM, MM)
Key Mechanisms	Abnormal plasma cell proliferation influenced by dietary patterns and obesity affecting risk and survival
Target Population	Individuals diagnosed with MGUS, SMM, or multiple myeloma
Care Setting	Outpatient settings with potential for dietary and lifestyle interventions

Higher Healthy Eating Index (HEI) scores correlate with reduced risk and mortality in plasma cell disorders.
Obesity is associated with lower diet quality, including reduced fiber and vegetable intake and increased added sugar consumption.
Education level influences diet quality, with higher education linked to better adherence to nutritional guidelines.

Assess dietary patterns using validated tools such as the Block Food Frequency Questionnaire in patients with plasma cell disorders.

Implement dietary interventions aimed at improving HEI scores, especially in patients with obesity.
Promote plant-based diets rich in whole grains, fruits, and vegetables to potentially reduce disease risk and improve outcomes.
Address health literacy and socioeconomic barriers to facilitate adherence to dietary guidelines.

Regularly evaluate dietary intake and HEI scores to monitor adherence and guide nutritional counseling.

High insulinemic and inflammatory diets rich in processed foods and added sugars increase risk and mortality in multiple myeloma.
Obesity increases risk of progression from MGUS to multiple myeloma and is linked with poorer dietary quality.

Patients with plasma cell disorders including MGUS, SMM, and multiple myeloma

Diet quality varies by BMI, sex, race/ethnicity, and education; targeted nutritional counseling may improve outcomes.

Use validated dietary assessment tools to evaluate patient nutrition.
Focus on improving diet quality in obese patients to potentially reduce disease progression and mortality.
Incorporate education on healthy eating patterns tailored to patient demographics and socioeconomic status.
Encourage increased intake of fiber, fruits, and vegetables while reducing added sugars.
Recognize sex and racial/ethnic differences in dietary habits to personalize interventions.

Clinical Scorecard: Nutritional Habits in Patients with Plasma Cell Disorders: Potential for Targeted Therapeutic Strategies