Establishing a Framework for National Monitoring of Hospital-Acquired Bacteremia and Fungemia
By
Gregory M. Schrank
September 9, 2026
Clinical Scorecard: Establishing a Framework for National Monitoring of Hospital-Acquired Bacteremia and Fungemia
At a Glance
Category Detail
Condition Hospital-onset bacteremia and fungemia (HOB)
Key Mechanisms Captures nosocomial bloodstream infections without regard to device presence or recent procedures.
Target Population Patients in acute-care hospitals.
Care Setting Hospital settings with a focus on infection surveillance.
Key Highlights
HAI rates in the US have improved, with a 27% reduction in prevalence since 2015. HOB serves as a new quality measure for bloodstream infections. The overall HOB rate was 2.07 events per 1000 patient-days in Ontario hospitals. Elevated HOB rates are associated with factors like long-term dialysis and active malignant neoplasm. Blood culture testing prevalence is linked to HOB incidence.
Guideline-Based Recommendations
Diagnosis
HOB defined as a positive blood culture for any bacterium or fungus obtained on or after hospital day 4.
Management
Monitor blood culture contamination in addition to true pathogens.
Monitoring & Follow-up
Incorporate patient and hospital characteristics in HOB surveillance models.
Risks
Insufficient risk adjustment may lead to underestimation of HAI events.
Patient & Prescribing Data
Patients admitted to acute-care hospitals.
Excessive antimicrobial exposure may occur due to blood culture contamination.
Clinical Best Practices
Utilize comprehensive data linkage for risk adjustment in HOB surveillance. Implement automated electronic data linkage to enhance quality measures.
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