Effect of stress-induced hyperglycaemia on clinical outcome in paitients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
By
Kaidong Zeng
Zhixiong Liao
Yanming Du
Jianping Ding
May 14, 2026
Clinical Scorecard: Impact of Stress-Induced Hyperglycemia on Clinical Outcomes in Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention
At a Glance
Category Detail
Condition Stress Hyperglycemia in STEMI Key Mechanisms Transient glycemic disturbance due to acute stress impacting prognosis. Target Population Patients with first-time STEMI undergoing PCI. Care Setting Emergency care and cardiology units.
Key Highlights
SHG is a strong independent risk factor for in-hospital all-cause mortality. Higher mortality and heart failure incidence observed in SHG patients at one year. SHG defined as FBG ≥7.0 mmol/L in non-diabetic patients with HbA1c < 6.5%. Acute hemodynamic instability may contribute to the association with SHG. Long-term prognosis primarily influenced by baseline cardiac function and coronary artery disease severity. Guideline-Based Recommendations
Diagnosis
SHG should be identified in non-diabetic STEMI patients with elevated FBG. Management
Develop individualized management strategies for acute-phase glucose fluctuations. Monitoring & Follow-up
Monitor blood glucose levels in STEMI patients to assess risk. Risks
Increased risk of in-hospital complications and long-term mortality associated with SHG. Patient & Prescribing Data
818 first-time STEMI patients undergoing PCI.
SHG patients showed significantly higher mortality rates and heart failure incidence.
Clinical Best Practices
Incorporate SHG into early risk stratification for STEMI patients. Utilize multivariate logistic regression for assessing prognosis. Related Resources & Content
