Feasibility and safety of an analgesia-first strategy without hypnotic sedatives in adult patients admitted to the intensive care unit after neurosurgical craniotomy: a protocol for a single-arm, single-center exploratory prospective study - Scorecard - MDSpire

Feasibility and safety of an analgesia-first strategy without hypnotic sedatives in adult patients admitted to the intensive care unit after neurosurgical craniotomy: a protocol for a single-arm, single-center exploratory prospective study

  • By

  • Yu-Mei Wang

  • Ying Tian

  • Shu-Ya Wang

  • Guang-Qiang Chen

  • Guang-Zhi Shi

  • June 10, 2026

  • 0 min

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Clinical Scorecard: Assessing the Safety and Feasibility of an Analgesia-First Approach Without Hypnotic Sedatives in Adult Neurosurgical Patients in the ICU: A Protocol for a Single-Arm, Exploratory Prospective Study

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationAdult patients after neurosurgical craniotomy with RASS score ≥ +1, excluding those requiring deep sedation.
Care Setting

Key Highlights

  • primary_endpoint

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

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      Risks

        Patient & Prescribing Data

        Remifentanil titrated from 0.1 to 0.2 μg/kg/min based on patient response and safety considerations.

        Clinical Best Practices

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        Original Source(s)

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