A comprehensive review and meta-analysis of the association between thyroid disorders and the risk of liver cancer development - Scorecard - MDSpire

A comprehensive review and meta-analysis of the association between thyroid disorders and the risk of liver cancer development

  • By

  • Omid Asbaghi

  • Ghazaleh Shimi

  • Arman Ghorbani

  • Hamid Zand

  • December 4, 2025

  • 0 min

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Clinical Scorecard: A comprehensive review and meta-analysis of the association between thyroid disorders and the risk of liver cancer development

At a Glance

CategoryDetail
Condition
Key MechanismsAltered hepatic metabolism, oxidative stress, mitochondrial dysfunction, and chronic inflammation (add references).
Target Population
Care Setting

Key Highlights

  • highlight_5

Guideline-Based Recommendations

Diagnosis

    Management

    • Monitor thyroid hormone levels in patients at risk for liver cancer.
    • Consider treatment options for thyroid disorders that may reduce liver cancer risk.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Adults with diagnosed hypothyroidism or hyperthyroidism.

        Thyroid hormone imbalances can influence liver cancer development.

        Clinical Best Practices

        • Conduct regular screenings for liver cancer in patients with thyroid disorders.
        • Utilize a multidisciplinary approach for managing patients with thyroid dysfunction and liver cancer risk.
        • Regularly monitor liver function tests in patients with thyroid disorders.

        References

        Original Source(s)

        A comprehensive review and meta-analysis of the association between thyroid disorders and the risk of liver cancer development

        • by Omid Asbaghi, Ghazaleh Shimi, Arman Ghorbani, Hamid Zand

        • December 4, 2025

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