Thoracoscopically assisted resection of left ventricular myxoma: a case report
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By
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Yuhui Zhang
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Fenlong Xue
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Mingzhen Qin
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Junshan Li
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Yanhe Ma
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Lianqun Wang
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Zhigang Guo
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May 20, 2026
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Clinical Scorecard: Case Report on Thoracoscopic Resection of a Myxoma in the Left Ventricle
At a Glance
| Category | Detail |
| Condition | |
| Key Mechanisms | Dysregulation of cAMP signaling pathways due to mutations in PRKAR1A and other genes, including PRKACA and PDE11A. |
| Target Population | |
| Care Setting | |
Key Highlights
- Cardiac myxoma is the most common primary benign cardiac tumor.
- Left ventricular myxomas are rare, accounting for 2%-3% of cases.
- Surgical resection is the preferred treatment to prevent recurrence.
- Multimodal imaging is crucial for accurate diagnosis and surgical planning.
- Video-assisted thoracoscopic surgery (VATS) can be a safe approach for resection.
- Misdiagnosis as left ventricular thrombus can lead to delayed treatment.
Guideline-Based Recommendations
Diagnosis
- Use transthoracic echocardiography (TTE) for initial visualization.
- Consider cardiac magnetic resonance (CMR) imaging for complex cases.
- Utilize myocardial contrast echocardiography (MCE) for assessing LV myxoma perfusion.
Management
- Surgical resection is the main treatment for cardiac myxomas.
Monitoring & Follow-up
- Monitor for complications such as embolism and heart failure post-surgery.
Risks
- Potential for misdiagnosis as left ventricular thrombus, leading to delayed treatment.
Patient & Prescribing Data
Successful thoracoscopic resection under cardiopulmonary bypass with good prognosis.
Clinical Best Practices
- Employ multimodal imaging to confirm diagnosis and assess tumor characteristics.
- Utilize VATS for minimally invasive surgical approaches when feasible.
- Maintain careful intraoperative monitoring to avoid complications.
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