Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation - Scorecard - MDSpire

Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation

  • By

  • Zoey Cho Ting Wong

  • Ivy Lynn Mak

  • Esther Yee Tak Yu

  • Emily Tsui Yee Tse

  • Julie Yun Chen

  • Weng Yee Chin

  • David Vai Kiong Chao

  • Wendy Wing Sze Tsui

  • Tony King Hang Ha

  • Eric Yuk Fai Wan

  • Cindy Lo Kuen Lam

  • August 4, 2025

  • 0 min

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Clinical Scorecard: Long-term Assessment of Hypertension-Related Complications Following a Decade of a Risk Assessment and Management Program: Insights from a Target Trial Emulation

At a Glance

CategoryDetail
ConditionHypertension (HT)
Key MechanismsRisk-stratified, multidisciplinary management including CVD risk assessment by trained nurses and tailored follow-up care supplementing usual primary care
Target PopulationPatients with hypertension without prior diabetes mellitus, end-stage renal disease, peripheral vascular disease, cardiovascular disease, or specialist outpatient attendance
Care SettingPublic general outpatient clinics (GOPCs) in Hong Kong primary care system

Key Highlights

  • RAMP-HT participants had a 9% reduced risk of cardiovascular diseases compared to usual care over 10 years.
  • RAMP-HT participants had a 12% reduced risk of all-cause mortality compared to usual care over 10 years.
  • The program integrates multidisciplinary interventions and risk stratification to enhance usual hypertension care in primary care.

Guideline-Based Recommendations

Diagnosis

  • Use trained nurses to perform cardiovascular disease risk assessments in hypertensive patients.

Management

  • Implement a protocol-driven, risk-stratified, multidisciplinary program supplementing usual care for hypertension management.
  • Provide risk-stratified follow-up care by nurses and allied health professionals based on individual CVD risk.

Monitoring & Follow-up

  • Long-term monitoring of cardiovascular outcomes and all-cause mortality to assess program effectiveness.

Risks

  • Consider potential biases in observational studies; target trial emulation can help mitigate immortal time and selection biases.

Patient & Prescribing Data

337,990 hypertensive patients without prior major comorbidities receiving care in primary care clinics.

Supplementing usual care with RAMP-HT multidisciplinary interventions is associated with significant reductions in cardiovascular events and mortality over 10 years.

Clinical Best Practices

  • Incorporate multidisciplinary teams including nurses and allied health professionals in hypertension management.
  • Use risk stratification to tailor follow-up intensity and interventions for hypertensive patients.
  • Integrate structured risk assessment protocols into routine primary care to improve long-term outcomes.
  • Leverage electronic health records for large-scale monitoring and evaluation of hypertension management programs.

References

Original Source(s)

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