Association between systemic inflammation response index and risk of major adverse cardiovascular events in adults with and without metabolic syndrome: a prospective cohort study in Shanghai, Pudong - Scorecard - MDSpire

Association between systemic inflammation response index and risk of major adverse cardiovascular events in adults with and without metabolic syndrome: a prospective cohort study in Shanghai, Pudong

  • By

  • Qiqi Meng

  • Juzhong Ke

  • Xiaonan Wang

  • Hua Qiu

  • Qingping Liu

  • Jiaojiao Gao

  • Jiahui Song

  • Yang Liu

  • Qian Xu

  • Mengyao Wu

  • Bo Huang

  • Yuling Qian

  • Lin Song

  • Xiaonan Ruan

  • Kang Wu

  • Yi Zhou

  • June 16, 2026

  • 0 min

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Clinical Scorecard: Link Between Systemic Inflammation Response Index and Major Adverse Cardiovascular Events Risk in Adults With and Without Metabolic Syndrome: Findings from a Prospective Cohort Study in Pudong, Shanghai

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target Population
Care SettingProspective cohort study in Pudong, Shanghai (2016-2019).

Key Highlights

  • Elevated SIRI is associated with increased MACE risk among participants with metabolic syndrome.
  • Participants with metabolic syndrome in the highest SIRI quartile have a significantly higher risk of MACE.

Guideline-Based Recommendations

Diagnosis

  • Assess SIRI as a potential biomarker for cardiovascular risk.

Management

  • Consider interventions targeting systemic inflammation in high-risk populations.

Monitoring & Follow-up

  • Monitor SIRI levels in patients with metabolic syndrome.

Risks

    Patient & Prescribing Data

    SIRI may be a biomarker for cardiovascular risk stratification.

    Clinical Best Practices

    • Utilize SIRI for cardiovascular risk assessment.

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    Original Source(s)

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