Neurological recovery after liver transplantation in a severely disabled adolescent with Wilson disease: a 1-year follow-up case report - Scorecard - MDSpire

Neurological recovery after liver transplantation in a severely disabled adolescent with Wilson disease: a 1-year follow-up case report

  • By

  • Konstantin Semash

  • Timur Dzhanbekov

  • Mansur Nasirov

  • Alla Syrkina

  • Bakhtiyarjon Umarov

  • June 17, 2026

  • 0 min

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Clinical Scorecard: Neurological Improvement Following Liver Transplantation in a Severely Impaired Adolescent with Wilson Disease: A One-Year Case Study Follow-Up

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationAdolescents with severe neurological impairment due to Wilson disease.
Care Setting

Key Highlights

  • Significant neurological improvement observed post-liver transplantation.
  • UWDRS score improved from 162 to 59 after one year.
  • Patient regained speech, cognitive engagement, and mobility.
  • Structured neuropsychosocial rehabilitation implemented.

Guideline-Based Recommendations

Diagnosis

    Management

    • Liver transplantation considered for patients with advanced Wilson disease and severe neurological deficits.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Adolescents with severe neurological impairment due to Wilson disease.

        D-penicillamine treatment adherence was poor prior to transplantation.

        Clinical Best Practices

        • Individualized decision-making regarding liver transplantation.
        • Continuous neuropsychosocial rehabilitation during recovery.

        Related Resources & Content

        Original Source(s)

        Neurological recovery after liver transplantation in a severely disabled adolescent with Wilson disease: a 1-year follow-up case report

        • by Konstantin Semash, Timur Dzhanbekov, Mansur Nasirov, Alla Syrkina, Bakhtiyarjon Umarov

        • June 17, 2026

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