Chest pain unit implementation in a multidisciplinary hospital: a retrospective observational study
By
Ayagyoz Umbetzhanova
Gulmira Derbissalina
Dias Vakpayev
Zhanagul Bekbergenova
Vitaliy Koikov
July 8, 2026
Clinical Scorecard: Establishment of a Chest Pain Unit in a Multidisciplinary Hospital: A Retrospective Observational Analysis
At a Glance
Category Detail
Condition Acute Coronary Syndrome (ACS)
Key Mechanisms Standardized assessment, electrocardiography, serial cardiac troponin measurements, HEART pathway risk stratification
Target Population Patients presenting with acute chest pain
Care Setting Multidisciplinary hospital emergency department
Key Highlights
Higher rates of AMI identification in CPU group (37.6% vs. 25.1%) Increased PCI use in CPU group (OR 1.43, p < 0.001) No significant difference in mortality between groups (2.4% vs. 2.2%) Higher direct treatment costs post-CPU implementation (p < 0.001) Diagnostic angiography more frequent in non-CPU group (OR 0.76, p = 0.02)
Guideline-Based Recommendations
Diagnosis
Utilize standardized diagnostic pathways including serial electrocardiography and cardiac biomarker testing
Management
Implement risk stratification tools like the HEART pathway for patient management
Monitoring & Follow-up
Monitor in-hospital outcomes and treatment costs following CPU implementation
Risks
Consider potential for increased treatment costs associated with CPU implementation
Patient & Prescribing Data
Patients with suspected ACS (ICD-10 I20–I22)
CPU pathways may improve diagnostic accuracy and management patterns
Clinical Best Practices
Adopt CPU protocols to optimize evaluation and management of acute chest pain Incorporate risk stratification tools to enhance patient safety and operational efficiency
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