Clinical Scorecard: Epidemiology of Cervical Cancer and Contributing Factors in HIV-Positive Women Attending Public Hospitals in Amhara Region, Ethiopia: A Cross-Sectional Analysis for 2025

At a Glance

Key Highlights

• Cervical cancer is the second most common malignancy among women globally.
• Women living with HIV are at significantly higher risk for cervical cancer.
• Low screening utilization among women living with HIV in Ethiopia.
• HPV vaccination and regular screening are critical for prevention.
• Cervical cancer is a leading cause of cancer-related morbidity and mortality in Ethiopian women.
• HPV vaccination is essential for reducing cervical cancer risk.

Guideline-Based Recommendations

Diagnosis

• Regular screening for cervical cancer in women living with HIV.
• HPV vaccination should be recommended for all eligible women living with HIV.

Management

• Timely treatment of precancerous lesions and invasive cervical cancer.
• Consideration of HPV vaccination as part of management.

Monitoring & Follow-up

• Monitor HPV infection rates and cervical cancer incidence among WLHIV.

Risks

• Increased risk factors include multiple sexual partners, early sexual activity, and immunosuppression.

Patient & Prescribing Data

Targeted screening and early detection are essential for improving outcomes; consider HPV vaccination as part of the treatment plan.

Clinical Best Practices

• Implement systematic cervical cancer screening programs.
• Promote HPV vaccination among women living with HIV.
• Enhance awareness and education regarding cervical cancer risks and prevention.
• Develop clear implementation strategies for screening programs.

References

• Cervical Cancer Epidemiology
• WHO Cervical Cancer Prevention Strategy
• HIV and Cervical Cancer Risk