Case Study: Co-occurrence of Persistent Fetal Vasculature and Lenticular Coloboma
-
By
-
Naiyu Sun
-
Jinchang Tian
-
Hong Zhang
-
July 10, 2026
Clinical Scorecard: Case Study: Co-occurrence of Persistent Fetal Vasculature and Lenticular Coloboma
At a Glance
| Category | Detail |
|---|
| Condition | Persistent Fetal Vasculature (PFV) |
| Key Mechanisms | Congenital ocular anomaly due to failure of normal regression of the fetal hyaloid vasculature. |
| Target Population | Young adults with congenital ocular anomalies. |
| Care Setting | Ophthalmology clinic |
Key Highlights
- PFV may cause various ocular anomalies including cataract and strabismus.
- The case presents a rare coexistence of PFV and lenticular coloboma.
- Anterior segment optical coherence tomography (AS-OCT) is crucial for diagnosis.
- Surgical management included cataract extraction and anterior vitrectomy.
- Capsular tension ring and intraocular lens (IOL) implantation were performed.
Guideline-Based Recommendations
Diagnosis
- Diagnosis of PFV relies on observation of persistent fetal vascular structures.
- B-scan ultrasonography is commonly used for definitive diagnosis.
Management
- Surgery is the main treatment, including anterior or posterior vitrectomy and lens extraction.
Monitoring & Follow-up
- Monitor for potential complications such as angle-closure glaucoma and retinal detachment.
Risks
- Serious complications may include hyphema, vitreous hemorrhage, and tractional retinal detachment.
Patient & Prescribing Data
23-year-old female with congenital cataract and PFV.
Optimized surgical strategies were applied for complex presentations.
Clinical Best Practices
- Utilize AS-OCT for detailed visualization of anterior segment anomalies.
- Consider capsular tension ring implantation during cataract surgery in PFV cases.
Related Resources & Content
