Case Report: Persistent fetal vasculature associated with lenticular coloboma
By
Naiyu Sun
Jinchang Tian
Hong Zhang
July 10, 2026
Clinical Scorecard: Case Study: Co-occurrence of Persistent Fetal Vasculature and Lenticular Coloboma
At a Glance
Category Detail
Condition Persistent Fetal Vasculature (PFV) Key Mechanisms Congenital ocular anomaly due to failure of normal regression of the fetal hyaloid vasculature. Target Population Young adults with congenital ocular anomalies. Care Setting Ophthalmology clinic
Key Highlights
PFV may cause various ocular anomalies including cataract and strabismus. The case presents a rare coexistence of PFV and lenticular coloboma. Anterior segment optical coherence tomography (AS-OCT) is crucial for diagnosis. Surgical management included cataract extraction and anterior vitrectomy. Capsular tension ring and intraocular lens (IOL) implantation were performed. Guideline-Based Recommendations
Diagnosis
Diagnosis of PFV relies on observation of persistent fetal vascular structures. B-scan ultrasonography is commonly used for definitive diagnosis. Management
Surgery is the main treatment, including anterior or posterior vitrectomy and lens extraction. Monitoring & Follow-up
Monitor for potential complications such as angle-closure glaucoma and retinal detachment. Risks
Serious complications may include hyphema, vitreous hemorrhage, and tractional retinal detachment. Patient & Prescribing Data
23-year-old female with congenital cataract and PFV.
Optimized surgical strategies were applied for complex presentations.
Clinical Best Practices
Utilize AS-OCT for detailed visualization of anterior segment anomalies. Consider capsular tension ring implantation during cataract surgery in PFV cases. Related Resources & Content
