Preoperative 7 T 3D Meniscal T2* Mapping Correlates With Postoperative Extrusion After Medial Meniscus Posterior Root Tear Repair - Scorecard - MDSpire
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Preoperative 7-T 3D Meniscal T2* Mapping Is Associated With Postrepair Extrusion in Medial Meniscus Posterior Root Tears

  • By

  • Abdul Wahed Kajabi

  • Karsten Knutsen

  • Eisa Hedayati

  • Collin Steinberger

  • Štefan Zbýň

  • Asif Abul Hassan

  • Hassan Ahad

  • Abhinav Lamba

  • Luke V. Tollefson

  • Takashi Takahashi

  • Gregor J. Metzger

  • Robert F. LaPrade

  • Jutta M. Ellermann

  • October 7, 2026

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Clinical Scorecard: Preoperative 7-T 3D Meniscal T2* Mapping Is Associated With Postrepair Extrusion in Medial Meniscus Posterior Root Tears

At a Glance

CategoryDetail
ConditionMedial meniscus posterior root tear (MMPRT), a tear associated with loss of hoop stress, meniscal extrusion, and increased tibiofemoral contact pressures.
Key MechanismsT2* relaxation time mapping reflects meniscal collagen fiber organization: organized circumferential fibers have shorter T2* values, while disorganized or degenerated fibers have longer values.
Target PopulationAdults aged 18 years or older with MRI- and arthroscopy-confirmed complete radial (type II) MMPRT undergoing root repair; age- and sex-comparable healthy controls were also enrolled.
Care SettingProspective clinical imaging and orthopedic surgical study using pre- and postrepair 7-T knee MRI and arthroscopic MMPRT repair.

Key Highlights

  • The study evaluated whether pre-repair 7-T 3D T2* measurements were associated with medial meniscal extrusion after MMPRT repair.
  • The study also compared T2* measurements before and after repair with measurements in age- and sex-matched healthy controls.
  • Prior histology-validated studies cited in the article associate higher T2* values with disorganized or degenerated meniscal collagen fibers.
  • Patients underwent two-tunnel transtibial root repair, with or without a centralization suture.
  • The supplied article text describes the study aims and methods but does not provide its results.

Guideline-Based Recommendations

Diagnosis

  • Study enrollment required MRI- and arthroscopy-confirmed complete radial (type II) MMPRT.
  • During arthroscopy, the surgeon assessed meniscal surface integrity and tear extent; surfaces were scored from 0 (smooth) to 3 (severe fibrillation).

Management

  • All enrolled patients underwent two-tunnel transtibial root repair, with or without a centralization suture.
  • The introduction states that nonoperative MMPRT management is associated with more rapid osteoarthritis development and elevated risk of total knee arthroplasty; this is background, not a guideline recommendation.

Monitoring & Follow-up

  • Patients received MRI before and after repair; healthy controls received one MRI using the same protocol.
  • KOOS surveys documented knee pain before repair and at follow-up 6–12 months after repair.

Risks

  • The introduction describes MMPRT as causing loss of hoop stress, outward meniscal extrusion, and increased tibiofemoral contact pressures.
  • The introduction reports an association between greater post-repair extrusion and more radiographic osteoarthritis progression.

Patient & Prescribing Data

Prospectively enrolled adults aged 18 years or older with complete radial (type II) MMPRT, pre-repair MRI, and follow-up MRI after repair; controls had no history of knee pathology or surgery.

Patients underwent two-tunnel transtibial root repair, with or without a centralization suture. The supplied text does not report treatment outcomes or medication prescribing data.

Clinical Best Practices

  • The study protocol used MRI and arthroscopy to confirm MMPRT and assess tear extent.
  • The study used 7-T 3D multi-echo gradient-recalled echo imaging for quantitative T2* mapping.
  • The MRI protocol positioned the main magnetic field approximately perpendicular to the meniscal superior–inferior surfaces to minimize the magic angle effect.
  • The article describes T2* as associated with collagen fiber organization; the supplied text does not establish a clinical threshold for decision-making.

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