Cutaneous SCC Trends Across Sex and Age - Scorecard - MDSpire

Cutaneous SCC Trends Across Sex and Age

  • By

  • Kathryn Wighton

  • February 2, 2026

  • 3 min

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Clinical Scorecard: Cutaneous SCC Trends Across Sex and Age

At a Glance

CategoryDetail
Condition
Key MechanismsIncreased incidence rates of carcinoma in situ and cSCC over time, with specific annual percentage changes.
Target Population
Care Setting

Key Highlights

  • cSCC incidence rates reached 131.6 per 100,000 person-years in males and 77.7 in females by 2023, with annual percentage increases of 2.6% and 3.1%, respectively.
  • Carcinoma in situ incidence increased significantly, with annual percentage changes of 6.4% in males and 5.8% in females, reaching 89.4 and 78.6 per 100,000 person-years by 2023.
  • KA incidence declined over the study period, reaching approximately 28 per 100,000 person-years.

Guideline-Based Recommendations

Diagnosis

    Management

    • Consideration of increasing incidence trends in clinical management and surveillance, including tailored follow-up strategies.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Patients aged 20 years or older with first-time diagnoses of cSCC, carcinoma in situ, or KA.

        Increased awareness and management strategies may be needed due to rising incidence rates.

        Clinical Best Practices

        • Acknowledge limitations in diagnostic practices and potential confounding factors, and recommend strategies to mitigate these issues.

        References

        Original Source(s)

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