Clinical and neurophysiological effects of manual acupuncture for upper-limb motor dysfunction after ischemic stroke: a three-arm randomized controlled trial - Scorecard - MDSpire
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Effects of Manual Acupuncture on Upper-Limb Motor Impairment Following Ischemic Stroke: Results from a Three-Group Randomized Controlled Study

  • By

  • Yu Min

  • Zhendong Huang

  • Ju Sun

  • Zetong Peng

  • Hongli Guan

  • Yuying Gong

  • Kaifeng Guo

  • August 25, 2026

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Clinical Scorecard: Effects of Manual Acupuncture on Upper-Limb Motor Impairment Following Ischemic Stroke: Results from a Three-Group Randomized Controlled Study

At a Glance

CategoryDetail
ConditionUpper-limb motor dysfunction following ischemic stroke
Key MechanismsManual acupuncture enhances neuroplasticity and neuromuscular activation
Target PopulationPatients with unilateral upper-limb impairment post-ischemic stroke
Care SettingSingle-center rehabilitation trial

Key Highlights

  • Manual acupuncture showed significant improvement in FMA-UE scores compared to conventional rehabilitation and sham acupuncture.
  • Greater MBI score improvements were observed with manual acupuncture.
  • Functional near-infrared spectroscopy indicated enhanced cortical activation with manual acupuncture.
  • Three mild adverse events were reported; no serious adverse events occurred.
  • Sham acupuncture did not significantly differ from conventional rehabilitation in most outcomes.

Guideline-Based Recommendations

Diagnosis

  • Assess upper-limb motor function using FMA-UE and MBI scores.

Management

  • Combine manual acupuncture with conventional rehabilitation for enhanced recovery.

Monitoring & Follow-up

  • Monitor for adverse events and functional improvements during treatment.

Risks

  • Mild subcutaneous bleeding may occur; serious adverse events are rare.

Patient & Prescribing Data

Individuals with unilateral upper-limb impairment within 3 months of ischemic stroke.

Manual acupuncture should be considered as an adjunct to conventional rehabilitation.

Clinical Best Practices

  • Initiate rehabilitation early and ensure it is coordinated and goal-oriented.
  • Utilize standardized acupuncture procedures in conjunction with rehabilitation.

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