Assessing the association of physical distancing to avoid COVID-19 with health-related quality of life in immunocompromised adolescents: results from the cross-sectional observational EAGLE study - Scorecard - MDSpire
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Assessing the association of physical distancing to avoid COVID-19 with health-related quality of life in immunocompromised adolescents: results from the cross-sectional observational EAGLE study
Clinical Scorecard: Evaluating the Link Between Physical Distancing Practices to Mitigate COVID-19 and Health-Related Quality of Life in Immunocompromised Adolescents: Findings from the EAGLE Cross-Sectional Study
At a Glance
Category
Detail
Condition
COVID-19 impact on health-related quality of life
Key Mechanisms
Physical distancing behaviors to avoid COVID-19
Target Population
Immunocompromised adolescents aged 13–17 years
Care Setting
Post-lockdown period in the United States and United Kingdom
Key Highlights
405 immunocompromised adolescents participated in the study.
Mean PDS-C19 T-score was 49.1, indicating moderate physical distancing intensity.
60.1% reported moderate and 16.3% reported high/very high physical distancing intensity.
Mean PedsQL™ score was 58.0, indicating moderate HRQoL.
Higher physical distancing intensity correlated with worse HRQoL and greater school impairment.
Guideline-Based Recommendations
Diagnosis
Assess physical distancing behaviors using the PDS-C19 scale.
Management
Encourage immunocompromised adolescents to practice risk-reducing behaviors.
Monitoring & Follow-up
Monitor HRQoL and mental health outcomes in relation to physical distancing.
Risks
Increased school and activity impairment associated with higher physical distancing.
Patient & Prescribing Data
Immunocompromised adolescents aged 13–17 years
Physical distancing behaviors may negatively impact HRQoL.
Clinical Best Practices
Implement supportive measures to address mental health in immunocompromised adolescents.
Encourage balanced approaches to physical distancing that consider HRQoL.
by Paul Williams, Timothy A. Herring, Renata T. C. Yokota, Sudhir Venkatesan, Klas Bergenheim, Johan L. Severens, Philip A. Powell, James C. Marcus, Stephanie Philpott, Sara Bestea, Jeffrey M. Rohay, Tiago Maia, Sylvia Taylor, Marieke Krol, James W. Varni
