Incidence and risk factors of post-transplant diabetes mellitus after kidney transplantation: a systematic review and meta-analysis - Scorecard - MDSpire

Incidence and risk factors of post-transplant diabetes mellitus after kidney transplantation: a systematic review and meta-analysis

  • By

  • Ni Chen

  • Yuli Chen

  • Qiuhong Liu

  • Ying Shu

  • May 25, 2026

  • 0 min

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Clinical Scorecard: Prevalence and Contributing Factors of Post-Transplant Diabetes Mellitus Following Kidney Transplantation: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
Condition
Key MechanismsImmunosuppressive regimens, particularly calcineurin inhibitors and glucocorticoids, contribute to PTDM risk.
Target Population
Care Setting

Key Highlights

  • Overall incidence of PTDM is approximately 20%.
  • Significant risk factors include advanced age, high BMI, family history of diabetes, high fasting plasma glucose, hypertriglyceridemia, and HCV infection.

Guideline-Based Recommendations

Diagnosis

  • Utilize consistent diagnostic criteria for PTDM.

Management

  • Consider individual risk factors for PTDM in immunosuppressive therapy.

Monitoring & Follow-up

  • Regular monitoring of metabolic status post-transplant.

Risks

  • PTDM can impair allograft function and increase cardiovascular event risk.

Patient & Prescribing Data

Patients undergoing kidney transplantation.

Immunosuppressive regimens may have diabetogenic effects.

Clinical Best Practices

    Related Resources & Content

    Original Source(s)

    Incidence and risk factors of post-transplant diabetes mellitus after kidney transplantation: a systematic review and meta-analysis

    • by Ni Chen, Yuli Chen, Qiuhong Liu, Ying Shu

    • May 25, 2026

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