Autoimmune GFAP astrocytopathy with eosinophils on cerebrospinal fluid cytology and isolated spinal cord lesions on MRI: a case report - Scorecard - MDSpire

Autoimmune GFAP astrocytopathy with eosinophils on cerebrospinal fluid cytology and isolated spinal cord lesions on MRI: a case report

  • By

  • Dongdong Zhang

  • Yahan Song

  • Yongjie Bai

  • Junqiang Yan

  • Ruile Shen

  • June 16, 2026

  • 0 min

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Clinical Scorecard: Eosinophilic Presence in Cerebrospinal Fluid Cytology and Isolated Spinal Cord Lesions on MRI in a Case of Autoimmune GFAP Astrocytopathy: A Case Study

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationAdults, specifically a case study of a 31-year-old woman with no prior medical history.
Care Setting

Key Highlights

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Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Follow-up MRI to assess resolution of spinal cord lesions at 1 month and 3 months post-treatment.

      Risks

        Patient & Prescribing Data

        Treatment with high-dose intravenous methylprednisolone for 5 days followed by an oral prednisone taper resulted in significant improvement.

        Clinical Best Practices

        • Evaluate CSF cytology for eosinophils in cases of suspected autoimmune disorders.
        • Perform comprehensive infectious studies, including PCR for viral pathogens, to rule out alternative diagnoses.

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