Efficacy and safety of transoral endoscopic thyroidectomy vestibular approach of papillary thyroid carcinoma: a network meta-analysis - Scorecard - MDSpire

Efficacy and safety of transoral endoscopic thyroidectomy vestibular approach of papillary thyroid carcinoma: a network meta-analysis

  • By

  • Pengyu Li

  • Kai Li

  • July 1, 2026

  • 0 min

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Clinical Scorecard: Assessment of the Safety and Effectiveness of the Transoral Endoscopic Thyroidectomy Vestibular Technique for Papillary Thyroid Carcinoma: A Network Meta-Analysis

At a Glance

CategoryDetail
ConditionPapillary Thyroid Carcinoma
Key MechanismsComparison of transoral endoscopic thyroidectomy vestibular approach (TOETVA), open thyroidectomy (OT), and endoscopic thyroidectomy via axillary breast approach (ABA) for surgical outcomes.
Target PopulationPatients diagnosed with papillary thyroid carcinoma.
Care SettingClinical evaluation of surgical techniques for thyroid cancer.

Key Highlights

  • TOETVA offers comparable surgical outcomes to OT and ABA with better parathyroid protection.
  • OT and ABA have shorter operative times compared to TOETVA.
  • No significant differences in tumor radicality or nerve injury among the three approaches.
  • TOETVA is superior to OT in preventing temporary hypoparathyroidism.
  • All approaches demonstrated safe and reliable clinical efficacy for PTC.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of papillary thyroid carcinoma should be confirmed through histopathological examination.

Management

  • Surgical resection remains the primary treatment for papillary thyroid carcinoma.

Monitoring & Follow-up

  • Postoperative monitoring for complications such as nerve injury and hypoparathyroidism is recommended.

Risks

  • Potential risks include temporary or permanent recurrent laryngeal nerve injury and hypoparathyroidism.

Patient & Prescribing Data

Patients with papillary thyroid carcinoma undergoing thyroidectomy.

TOETVA is a feasible alternative to traditional open thyroidectomy, offering aesthetic benefits.

Clinical Best Practices

  • Consider TOETVA for patients seeking minimally invasive options with good cosmetic outcomes.
  • Evaluate individual patient factors when selecting surgical approach.

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