Assessing the Impact of Systemic Hypertension on Retinal Microvasculature, Optic Nerve Head, and Visual Fields Through Optical Coherence Tomography Angiography and Visual Field Analysis - Scorecard - MDSpire
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Assessing the Impact of Systemic Hypertension on Retinal Microvasculature, Optic Nerve Head, and Visual Fields Through Optical Coherence Tomography Angiography and Visual Field Analysis

  • By

  • Salma Maged Mohammed Mohammed El-Maghrabi

  • Rafik Mohamed Fouad El Ghazawy

  • Hisham Mohamed Khairy Abdel Dayem

  • Al Hussein Aly Mohamed Swelem

  • Passant Sayed Saif

  • November 21, 2025

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Clinical Scorecard: Assessing the Impact of Systemic Hypertension on Retinal Microvasculature, Optic Nerve Head, and Visual Fields Through Optical Coherence Tomography Angiography and Visual Field Analysis

At a Glance

CategoryDetail
ConditionSystemic Hypertension
Key MechanismsAnatomical and functional changes in microcirculation, including microvascular rarefaction and reduced circulatory efficiency.
Target PopulationAdults aged 40 years or more with primary hypertension.
Care SettingOphthalmology outpatient clinic.

Key Highlights

  • Retinal microvasculature serves as a biomarker for systemic vascular disorders.
  • OCTA enables documentation of hypertensive retinopathy stages.
  • Longer duration of hypertension correlates with significant reductions in vessel density.
  • Visual field assessment is crucial for evaluating functional complications of systemic diseases.
  • Structure-function correlations may support OCTA as a noninvasive biomarker.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of primary hypertension based on WHO criteria (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg).

Management

  • Monitor vascular density and visual field indices in hypertensive patients.

Monitoring & Follow-up

  • Use OCTA and visual field analysis for early detection of hypertensive end-organ damage.

Risks

  • Increased risk of coronary heart disease, stroke, and end-stage renal disease associated with systemic hypertension.

Patient & Prescribing Data

Patients aged 40 years or older with established primary hypertension.

Consider duration of hypertension and antihypertensive medication types in management.

Clinical Best Practices

  • Utilize SS-OCTA for detailed assessment of retinal and choroidal microvasculature.
  • Incorporate visual field testing as part of routine evaluation for hypertensive patients.

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