Author Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial - Scorecard - MDSpire
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Correction: Toripalimab or placebo with chemotherapy as initial therapy for advanced nasopharyngeal carcinoma in a multicenter, randomized phase 3 trial

  • By

  • Hai-Qiang Mai

  • Qiu-Yan Chen

  • Dongping Chen

  • Chaosu Hu

  • Kunyu Yang

  • Jiyu Wen

  • Jingao Li

  • Ying-Rui Shi

  • Feng Jin

  • Ruilian Xu

  • Jianji Pan

  • Shenhong Qu

  • Ping Li

  • Chunhong Hu

  • Yi-Chun Liu

  • Yi Jiang

  • Xia He

  • Hung-Ming Wang

  • Wan-Teck Lim

  • Wangjun Liao

  • Xiaohui He

  • Xiaozhong Chen

  • Zhigang Liu

  • Xianglin Yuan

  • Qi Li

  • Xiaoyan Lin

  • Shanghua Jing

  • Yanju Chen

  • Yin Lu

  • Ching-Yun Hsieh

  • Muh-Hwa Yang

  • Chia-Jui Yen

  • Jens Samol

  • Hui Feng

  • Sheng Yao

  • Patricia Keegan

  • Rui-Hua Xu

  • October 27, 2026

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Clinical Scorecard: Correction: Toripalimab or placebo with chemotherapy as initial therapy for advanced nasopharyngeal carcinoma

At a Glance

CategoryDetail
ConditionAdvanced nasopharyngeal carcinoma
Key MechanismsThe correction reports no treatment mechanisms; it addresses errors and clarifications in a randomized phase 3 trial of toripalimab or placebo with chemotherapy.
Target PopulationPatients enrolled in the multicenter randomized phase 3 trial of initial therapy for advanced nasopharyngeal carcinoma.
Care SettingCorrection to published trial results, tables, figures, and source data.

Key Highlights

  • The corrected number of patients continuing maintenance treatment after chemotherapy is 233 (80.6%), not 231 (79.9%); the Extended Data Fig. 1 total is also 233.
  • The Fig. 2 data cutoff date is 18 February 2021, not 18 February 2020.
  • Corrected Toripalimab + GP safety values include any-grade thrombocytopenia in 92 (63.0%) and grade ≥3 hypochloremia in 2 (1.4%).
  • The Supplementary Table S10 footnote should read “determined by BIRC,” not “determined by investigator.”
  • Supplementary Table S13 reports Alive as 219 (75.8%), not 219 (76.1%); the Source Data Fig. 2 column should be labeled OS, not PFS.
  • In source data for Figs. 1, 2 and Extended Data Fig. 2, 0 denotes an event and 1 denotes censoring.
  • The correction states that the study results and conclusions are unaffected.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

        Risks

          Patient & Prescribing Data

          Trial participants with advanced nasopharyngeal carcinoma; the correction does not provide prescribing guidance.

          The correction concerns toripalimab or placebo with chemotherapy and reports that the study results and conclusions remain unaffected.

          Clinical Best Practices

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            Original Source(s)

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