Assessment of cardioprotective activity of a nitrate enriched food-based polyherbal formulation using experimental myocardial infarction in rats
By
Sruthi Ramagiri
Hemraj Singh
Rajeev Taliyan
Yogendra Kumar Choudhary
Iwin Joseph Benny
July 10, 2026
Clinical Scorecard: Evaluation of the Cardioprotective Effects of a Nitrate-Rich Herbal Food Formulation in a Rat Model of Myocardial Infarction
At a Glance
Category Detail
Condition Myocardial Infarction
Key Mechanisms Nitrate/NO-related mechanisms, attenuation of oxidative stress, suppression of inflammatory pathways
Target Population Wistar rats
Care Setting In vivo model of myocardial infarction
Key Highlights
Oxystorm and turmeric extract reduced cardiac injury biomarkers. Treatment alleviated oxidative stress and inflammation.
Guideline-Based Recommendations
Diagnosis
Assessment of cardiac injury biomarkers such as LDH, CK-MB, myoglobin, and troponin I.
Management
Monitoring & Follow-up
Monitoring levels of inflammatory biomarkers like interleukin-6 and TNF-α.
Risks
Potential for increased oxidative stress and cardiac inflammation if untreated.
Patient & Prescribing Data
Not specified; study conducted on Wistar rats.
Oxystorm combined with turmeric extract may enhance cardioprotective effects.
Clinical Best Practices
Incorporate dietary modifications with nitrate-rich foods for cardiovascular health. Utilize herbal formulations alongside conventional therapies for enhanced outcomes.
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