Assessment of cardioprotective activity of a nitrate enriched food-based polyherbal formulation using experimental myocardial infarction in rats - Scorecard - MDSpire

Assessment of cardioprotective activity of a nitrate enriched food-based polyherbal formulation using experimental myocardial infarction in rats

  • By

  • Sruthi Ramagiri

  • Hemraj Singh

  • Rajeev Taliyan

  • Yogendra Kumar Choudhary

  • Iwin Joseph Benny

  • July 10, 2026

  • 0 min

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Clinical Scorecard: Evaluation of the Cardioprotective Effects of a Nitrate-Rich Herbal Food Formulation in a Rat Model of Myocardial Infarction

At a Glance

CategoryDetail
ConditionMyocardial Infarction
Key MechanismsNitrate/NO-related mechanisms, attenuation of oxidative stress, suppression of inflammatory pathways
Target PopulationWistar rats
Care SettingIn vivo model of myocardial infarction

Key Highlights

  • Oxystorm and turmeric extract reduced cardiac injury biomarkers.
  • Treatment alleviated oxidative stress and inflammation.

Guideline-Based Recommendations

Diagnosis

  • Assessment of cardiac injury biomarkers such as LDH, CK-MB, myoglobin, and troponin I.

Management

    Monitoring & Follow-up

    • Monitoring levels of inflammatory biomarkers like interleukin-6 and TNF-α.

    Risks

    • Potential for increased oxidative stress and cardiac inflammation if untreated.

    Patient & Prescribing Data

    Not specified; study conducted on Wistar rats.

    Oxystorm combined with turmeric extract may enhance cardioprotective effects.

    Clinical Best Practices

    • Incorporate dietary modifications with nitrate-rich foods for cardiovascular health.
    • Utilize herbal formulations alongside conventional therapies for enhanced outcomes.

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