Effectiveness of transcutaneous auricular vagus nerve stimulation in stroke rehabilitation: a systematic review and meta-analysis of randomized clinical trials - Scorecard - MDSpire

Effectiveness of transcutaneous auricular vagus nerve stimulation in stroke rehabilitation: a systematic review and meta-analysis of randomized clinical trials

  • By

  • Shuaijing Wan

  • Xiaolu Liu

  • Wenjing Jiang

  • Zesen Li

  • Zhexuan Yan

  • Weibo Li

  • Yu Yin

  • May 4, 2026

  • 0 min

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Clinical Scorecard: Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Stroke Recovery: A Systematic Review and Meta-Analysis of Randomized Trials

At a Glance

CategoryDetail
ConditionStroke recovery
Key MechanismsTranscutaneous auricular vagus nerve stimulation (taVNS) enhances neuroplasticity and functional recovery.
Target PopulationAdults over 18 years with a clinical diagnosis of an initial stroke.
Care SettingClinical rehabilitation settings.

Key Highlights

  • taVNS significantly improves motor function, psychological well-being, and activities of daily living (ADL) in stroke patients.
  • The effectiveness of taVNS is influenced by stimulation frequency, current strength, and treatment duration.
  • Subgroup analysis shows better outcomes with 20 Hz taVNS and at least 10 sessions.
  • The study includes data from 10 randomized controlled trials with 512 participants.
  • taVNS is a noninvasive alternative to conventional vagus nerve stimulation.

Guideline-Based Recommendations

Diagnosis

  • Clinical diagnosis of stroke in adults over 18 years.

Management

  • Consider taVNS as an adjunct therapy in stroke rehabilitation.

Monitoring & Follow-up

  • Assess motor function, psychological well-being, and ADL scores regularly.

Risks

  • Monitor for potential side effects associated with taVNS.

Patient & Prescribing Data

Adults with stroke in various recovery stages (acute, subacute, chronic).

taVNS should be administered with optimal parameters (20 Hz, at least 10 sessions) for best outcomes.

Clinical Best Practices

  • Integrate taVNS with conventional rehabilitation therapies.
  • Tailor stimulation parameters to individual patient needs.
  • Conduct regular assessments to evaluate treatment efficacy.

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