Age-stratified diagnostic performance of the ovarian-adnexal reporting and data system for adnexal masses: a focus on school-age children, early, and middle adolescents - Scorecard - MDSpire

Age-stratified diagnostic performance of the ovarian-adnexal reporting and data system for adnexal masses: a focus on school-age children, early, and middle adolescents

  • By

  • Rongsen Zhang

  • Yan Tan

  • Xiaoye Zhang

  • Taiqing Zheng

  • Minghui Liu

  • Guotao Wang

  • July 15, 2026

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Clinical Scorecard: Evaluation of Ovarian-Adnexal Reporting and Data System Diagnostic Efficacy for Adnexal Masses in Pediatric Age Groups: Emphasis on School-Aged Children and Adolescents

At a Glance

CategoryDetail
ConditionAdnexal masses in pediatric populations
Key MechanismsOvarian-Adnexal Reporting and Data System (O-RADS) ultrasound classification
Target PopulationPediatric patients aged 6-17 years
Care SettingGynecological ultrasound examination

Key Highlights

  • O-RADS demonstrated 100% sensitivity and 93.6% specificity in school-age children.
  • Sensitivity decreased to 88.2% and specificity to 85.6% in middle adolescents.
  • Positive predictive value (PPV) dropped from 71.4% in school-age children to 29.4% in middle adolescents.
  • Significant difference in AUC between middle adolescents and school-age children (P = 0.027).
  • Age-specific considerations are crucial for applying O-RADS in pediatric populations.

Guideline-Based Recommendations

Diagnosis

  • Utilize O-RADS ultrasound lexicon for classification of adnexal masses.

Management

  • Consider age-specific diagnostic performance when evaluating adnexal masses.

Monitoring & Follow-up

  • Monitor changes in diagnostic performance across different pediatric age groups.

Risks

  • Be aware of the lower pretest probability of malignancy in pediatric populations.

Patient & Prescribing Data

501 pediatric patients with adnexal masses

Histological confirmation via surgery or biopsy is necessary for diagnosis.

Clinical Best Practices

  • Implement standardized assessment protocols using O-RADS for pediatric adnexal masses.
  • Ensure radiologists are trained in the O-RADS classification system.

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