Case Report: Clinicopathological features and outcomes of superficial cervicovaginal myofibroblastoma: analysis of two cases and a review of the literature - Scorecard - MDSpire

Case Report: Clinicopathological features and outcomes of superficial cervicovaginal myofibroblastoma: analysis of two cases and a review of the literature

  • By

  • Xiaoli Cai

  • Yanli Liu

  • Yunfeng Niu

  • Xiaodan Shen

  • Qian Zhang

  • Lei Liang

  • Shuang Liu

  • May 13, 2026

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Clinical Scorecard: Clinical Insights and Outcomes of Superficial Cervicovaginal Myofibroblastoma: A Report on Two Cases and Literature Review

At a Glance

CategoryDetail
ConditionSuperficial cervicovaginal myofibroblastoma (SCVM)
Key MechanismsBenign mesenchymal tumor arising from the superficial stromal layer of the submucosal vagina and cervix.
Target PopulationWomen aged 20–60 years.
Care SettingGynecological clinics and surgical settings.

Key Highlights

  • SCVM is clinically rare, representing less than 0.1% of benign tumors.
  • Common symptoms include irregular vaginal bleeding and incidental findings.
  • Surgical excision is the primary treatment with a favorable prognosis and low recurrence rate.
  • Accurate diagnosis requires histopathological and immunohistochemical evaluation.
  • The tumor demonstrates hormone-related characteristics and slow growth.

Guideline-Based Recommendations

Diagnosis

  • Utilize integrated evaluation of histopathological morphology and immunohistochemical profiles.

Management

  • Surgical resection is recommended as the primary treatment approach.

Monitoring & Follow-up

  • Follow-up periods should be conducted to monitor for recurrence, typically ranging from 6 months to 1 year.

Risks

  • Misdiagnosis or overtreatment due to overlapping features with other soft tissue tumors.

Patient & Prescribing Data

Female patients aged 20–60 years with SCVM.

Surgical excision is effective with no reported recurrence in follow-up.

Clinical Best Practices

  • Conduct thorough gynecological examinations to identify incidental findings.
  • Employ imaging techniques like gynecological ultrasonography for initial assessment.
  • Ensure comprehensive pathological analysis to differentiate SCVM from other tumors.

Related Resources & Content

Original Source(s)

Case Report: Clinicopathological features and outcomes of superficial cervicovaginal myofibroblastoma: analysis of two cases and a review of the literature

  • by Xiaoli Cai, Yanli Liu, Yunfeng Niu, Xiaodan Shen, Qian Zhang, Lei Liang, Shuang Liu

  • May 13, 2026

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