Assessment of Corneal Biomechanical Properties Following SMILE and LASEK in Patients with Moderate to High Myopia and Thin Corneas: A Retrospective Comparative Analysis - Scorecard - MDSpire
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Assessment of Corneal Biomechanical Properties Following SMILE and LASEK in Patients with Moderate to High Myopia and Thin Corneas: A Retrospective Comparative Analysis

  • By

  • Ran Zhang

  • Yunlong Zhong

  • Hongxi Wu

  • Yuantu You

  • Xiaohan Su

  • Yusheng Li

  • Xingtao Zhou

  • Nanye Wang

  • February 25, 2026

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Clinical Scorecard: Assessment of Corneal Biomechanical Properties Following SMILE and LASEK in Patients with Moderate to High Myopia and Thin Corneas: A Retrospective Comparative Analysis

At a Glance

CategoryDetail
ConditionModerate to high myopia with thin corneas (CCT ≤ 530 μm)
Key MechanismsEvaluation of corneal biomechanical properties post-surgery using metrics like bIOP, SP-A1, IntInv-Rad, DAR 2.0 mm, and ARTh.
Target PopulationPatients aged > 18 years with myopia and thin corneas
Care SettingOphthalmology clinics performing corneal refractive surgery

Key Highlights

  • SMILE and LASEK induce fewer biomechanical changes compared to LASIK.
  • Study focuses on corneas with CCT ≤ 530 μm, a transitional thickness range.
  • Long-term biomechanical stability is critical for surgical success, evaluated at 2 years post-op.

Guideline-Based Recommendations

Diagnosis

  • Comprehensive preoperative ophthalmic examination including corneal topography and biomechanics.

Management

  • Select surgical technique based on corneal characteristics and patient expectations.

Monitoring & Follow-up

  • Evaluate corneal biomechanical properties at 2 years to assess stability and risk of ectasia.

Risks

  • Iatrogenic keratectasia is a significant concern in patients with thin corneas.

Patient & Prescribing Data

47 patients (47 eyes) with moderate to high myopia and thin corneas.

SMILE preferred for sufficient corneal thickness; LASEK for thinner corneas and specific occupational needs.

Clinical Best Practices

  • Utilize shared decision-making for surgical technique selection.
  • Monitor postoperative healing and biomechanical stability over 2 years.

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